BIOMAT Database Logo BIOMAT Database Logo

Effects of diets rich in monounsaturated fatty acids on plasma lipoproteins--the Jerusalem Nutrition Study. II. Monounsaturated fatty acids vs carbohydrates. 1992

E M Berry, and S Eisenberg, and Y Friedlander, and D Harats, and N A Kaufmann, and Y Norman, and Y Stein
Department of Medicine, Hadassah University Hospital, Jerusalem, Israel.

Seventeen male Yeshiva students were randomly allocated to a crossover study with two 12-wk dietary periods of monounsaturated fatty acids (MUFAs) vs a carbohydrate (CHO)-rich diet while concentrations of saturated (SFAs) and polyunsaturated (PUFAs) fatty acids were kept similar. Total plasma cholesterol (TC) decreased significantly by approximately 7.7% and low-density-lipoprotein cholesterol (LDL-C) by 14.4% on the MUFA diet, whereas on the CHO diet no significant change in cholesterol concentrations occurred, in contrast to that predicted by the equations of Keys and Hegsted. Concentrations of high-density-lipoprotein cholesterol (HDL-C) did not change significantly on either diet. On the MUFA diet there was a significantly lower proneness to peroxidation of plasma and LDL lipids and less extensive metabolism of conditioned LDL by peritoneal macrophages. We conclude that dietary MUFAs lower TC and LDL-C concentrations, independently of other dietary fatty acids and in addition may reduce the susceptibility of LDL to oxidative stress.

UI MeSH Term Description Entries
D008074 Lipoproteins Lipid-protein complexes involved in the transportation and metabolism of lipids in the body. They are spherical particles consisting of a hydrophobic core of TRIGLYCERIDES and CHOLESTEROL ESTERS surrounded by a layer of hydrophilic free CHOLESTEROL; PHOSPHOLIPIDS; and APOLIPOPROTEINS. Lipoproteins are classified by their varying buoyant density and sizes. Circulating Lipoproteins,Lipoprotein,Lipoproteins, Circulating
D008076 Cholesterol, HDL Cholesterol which is contained in or bound to high-density lipoproteins (HDL), including CHOLESTEROL ESTERS and free cholesterol. High Density Lipoprotein Cholesterol,Cholesterol, HDL2,Cholesterol, HDL3,HDL Cholesterol,HDL(2) Cholesterol,HDL(3) Cholesterol,HDL2 Cholesterol,HDL3 Cholesterol,alpha-Lipoprotein Cholesterol,Cholesterol, alpha-Lipoprotein,alpha Lipoprotein Cholesterol
D008078 Cholesterol, LDL Cholesterol which is contained in or bound to low density lipoproteins (LDL), including CHOLESTEROL ESTERS and free cholesterol. LDL Cholesterol,Cholesteryl Linoleate, LDL,LDL Cholesteryl Linoleate,Low Density Lipoprotein Cholesterol,beta-Lipoprotein Cholesterol,Cholesterol, beta-Lipoprotein,beta Lipoprotein Cholesterol
D008297 Male Males
D011897 Random Allocation A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects. Randomization,Allocation, Random
D001835 Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. Body Weights,Weight, Body,Weights, Body
D002784 Cholesterol The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils. Epicholesterol
D004040 Dietary Carbohydrates Carbohydrates present in food comprising digestible sugars and starches and indigestible cellulose and other dietary fibers. The former are the major source of energy. The sugars are in beet and cane sugar, fruits, honey, sweet corn, corn syrup, milk and milk products, etc.; the starches are in cereal grains, legumes (FABACEAE), tubers, etc. (From Claudio & Lagua, Nutrition and Diet Therapy Dictionary, 3d ed, p32, p277) Carbohydrates, Dietary,Carbohydrate, Dietary,Dietary Carbohydrate
D004042 Dietary Fats, Unsaturated Unsaturated fats or oils used in foods or as a food. Dietary Oils,Unsaturated Dietary Fats,Dietary Fat, Unsaturated,Dietary Oil,Fat, Unsaturated Dietary,Fats, Unsaturated Dietary,Oil, Dietary,Oils, Dietary,Unsaturated Dietary Fat
D004910 Erythrocyte Membrane The semi-permeable outer structure of a red blood cell. It is known as a red cell 'ghost' after HEMOLYSIS. Erythrocyte Ghost,Red Cell Cytoskeleton,Red Cell Ghost,Erythrocyte Cytoskeleton,Cytoskeleton, Erythrocyte,Cytoskeleton, Red Cell,Erythrocyte Cytoskeletons,Erythrocyte Ghosts,Erythrocyte Membranes,Ghost, Erythrocyte,Ghost, Red Cell,Membrane, Erythrocyte,Red Cell Cytoskeletons,Red Cell Ghosts

Related Publications

E M Berry, and S Eisenberg, and Y Friedlander, and D Harats, and N A Kaufmann, and Y Norman, and Y Stein
Monounsaturated fatty acids-rich diets in hypercholesterolemic-growing rats.
January 2015, International journal of food sciences and nutrition,
E M Berry, and S Eisenberg, and Y Friedlander, and D Harats, and N A Kaufmann, and Y Norman, and Y Stein
The effects of polyunsaturated fat vs monounsaturated fat on plasma lipoproteins.
May 1990, JAMA,
E M Berry, and S Eisenberg, and Y Friedlander, and D Harats, and N A Kaufmann, and Y Norman, and Y Stein
Effects of monounsaturated fatty acids v complex carbohydrates on serum lipoproteins and apoproteins in healthy men and women.
February 1989, Metabolism: clinical and experimental,
E M Berry, and S Eisenberg, and Y Friedlander, and D Harats, and N A Kaufmann, and Y Norman, and Y Stein
Effects of diets rich in saturated fatty acids with or without added cholesterol on plasma lipids and lipoproteins.
November 1970, Lipids,
E M Berry, and S Eisenberg, and Y Friedlander, and D Harats, and N A Kaufmann, and Y Norman, and Y Stein
Comparison of monounsaturated fatty acids and carbohydrates for lowering plasma cholesterol.
March 1986, The New England journal of medicine,
E M Berry, and S Eisenberg, and Y Friedlander, and D Harats, and N A Kaufmann, and Y Norman, and Y Stein
Effect of dietary monounsaturated fatty acids on plasma lipoproteins and apolipoproteins in women.
July 1992, The American journal of clinical nutrition,
E M Berry, and S Eisenberg, and Y Friedlander, and D Harats, and N A Kaufmann, and Y Norman, and Y Stein
Effects on plasma lipoproteins of monounsaturated, saturated, and polyunsaturated fatty acids in the diet of African green monkeys.
October 1990, Journal of lipid research,
E M Berry, and S Eisenberg, and Y Friedlander, and D Harats, and N A Kaufmann, and Y Norman, and Y Stein
Effect of monounsaturated fatty acids versus complex carbohydrates on high-density lipoproteins in healthy men and women.
January 1987, Lancet (London, England),
E M Berry, and S Eisenberg, and Y Friedlander, and D Harats, and N A Kaufmann, and Y Norman, and Y Stein
The effects of polyunsaturated fat vs monounsaturated fat on plasma lipoproteins: the power of a study.
January 1990, JAMA,
E M Berry, and S Eisenberg, and Y Friedlander, and D Harats, and N A Kaufmann, and Y Norman, and Y Stein
Effects of dietary monounsaturated fatty acids on plasma lipids in humans.
December 1990, Journal of lipid research,
Copied contents to your clipboard!