-transparent.png){kind=logo}
Synthesis of 9-[1-(substituted)-2-(phosphonomethoxy)ethyl]adenine derivatives as possible antiviral agents. 2005
Minwan Wu, and
Yahya El-Kattan, and
Tsu-Hsing Lin, and
Ajit Ghosh, and
V Satish Kumar, and
Pravin L Kotian, and
Xiaogang Cheng, and
Shanta Bantia, and
Yarlagadda S Babu, and
Pooran Chand
BioCryst Pharmaceuticals, Inc., Birmingham, Alabama 35244, USA.
Various C-1'-substituted acyclic N9 adenine nucleosides were prepared from 9-[(1-hydroxymethyl)(3-monomethoxytrityloxy)propyl]-N6-monomethoxytrityladenine. The hydroxymethyl was modified to the phosphonomethoxy derivative, and the 3-monomethoxytrityloxy was converted to hydroxyl, methoxy, azido, and amino. Other substituents, such as ethyl and ea-hydroxyethyl were also prepared. The resulting phosphonomethoxy derivatives were converted to prodrugs.
Related Publications
Minwan Wu, and
Yahya El-Kattan, and
Tsu-Hsing Lin, and
Ajit Ghosh, and
V Satish Kumar, and
Pravin L Kotian, and
Xiaogang Cheng, and
Shanta Bantia, and
Yarlagadda S Babu, and
Pooran Chand
September 1993,
Journal of medicinal chemistry,
Minwan Wu, and
Yahya El-Kattan, and
Tsu-Hsing Lin, and
Ajit Ghosh, and
V Satish Kumar, and
Pravin L Kotian, and
Xiaogang Cheng, and
Shanta Bantia, and
Yarlagadda S Babu, and
Pooran Chand
August 1992,
Journal of medicinal chemistry,
Minwan Wu, and
Yahya El-Kattan, and
Tsu-Hsing Lin, and
Ajit Ghosh, and
V Satish Kumar, and
Pravin L Kotian, and
Xiaogang Cheng, and
Shanta Bantia, and
Yarlagadda S Babu, and
Pooran Chand
August 1996,
Journal of medicinal chemistry,
Minwan Wu, and
Yahya El-Kattan, and
Tsu-Hsing Lin, and
Ajit Ghosh, and
V Satish Kumar, and
Pravin L Kotian, and
Xiaogang Cheng, and
Shanta Bantia, and
Yarlagadda S Babu, and
Pooran Chand
December 2006,
Journal of medicinal chemistry,
Minwan Wu, and
Yahya El-Kattan, and
Tsu-Hsing Lin, and
Ajit Ghosh, and
V Satish Kumar, and
Pravin L Kotian, and
Xiaogang Cheng, and
Shanta Bantia, and
Yarlagadda S Babu, and
Pooran Chand
December 2004,
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry,
Minwan Wu, and
Yahya El-Kattan, and
Tsu-Hsing Lin, and
Ajit Ghosh, and
V Satish Kumar, and
Pravin L Kotian, and
Xiaogang Cheng, and
Shanta Bantia, and
Yarlagadda S Babu, and
Pooran Chand
June 1994,
Journal of medicinal chemistry,
Minwan Wu, and
Yahya El-Kattan, and
Tsu-Hsing Lin, and
Ajit Ghosh, and
V Satish Kumar, and
Pravin L Kotian, and
Xiaogang Cheng, and
Shanta Bantia, and
Yarlagadda S Babu, and
Pooran Chand
January 2000,
Metal-based drugs,
Minwan Wu, and
Yahya El-Kattan, and
Tsu-Hsing Lin, and
Ajit Ghosh, and
V Satish Kumar, and
Pravin L Kotian, and
Xiaogang Cheng, and
Shanta Bantia, and
Yarlagadda S Babu, and
Pooran Chand
January 2018,
Antiviral chemistry & chemotherapy,
Minwan Wu, and
Yahya El-Kattan, and
Tsu-Hsing Lin, and
Ajit Ghosh, and
V Satish Kumar, and
Pravin L Kotian, and
Xiaogang Cheng, and
Shanta Bantia, and
Yarlagadda S Babu, and
Pooran Chand
August 2015,
ChemMedChem,
Minwan Wu, and
Yahya El-Kattan, and
Tsu-Hsing Lin, and
Ajit Ghosh, and
V Satish Kumar, and
Pravin L Kotian, and
Xiaogang Cheng, and
Shanta Bantia, and
Yarlagadda S Babu, and
Pooran Chand
December 1996,
Journal of medicinal chemistry,
