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HER-2 codon 655 polymorphism together with human papillomavirus (HPV) types were examined in a total of 279 cervical smear samples. Forty-nine patients with high-grade squamous intraepithelial lesion had higher frequency of high-risk HPV than 167 patients with low-grade squamous intraepithelial lesion and 63 controls. There was no statistical difference in the frequencies of HER-2 Ile/Ile, Ile/Val, and Val/Val genotypes between squamous intraepithelial lesions (SILs) and controls. When the Ile/Ile genotype was compared to the Ile/Val + Val/Val genotypes, there was also no statistical difference in the genotype prevalence between SILs and controls either in 91 or 188 patients with or without high-risk HPV, respectively. These results suggest that the HER-2 polymorphism at codon 655 in cervical cell samples is unlikely to be associated with HPV status and the onset of cervical cancer in a Japanese population.
M Ueda, and
Y-C Hung, and
Y Terai, and
J Saito, and
O Nunobiki, and
S Noda, and
M Ueki
March 2011,
Genetic testing and molecular biomarkers,
M Ueda, and
Y-C Hung, and
Y Terai, and
J Saito, and
O Nunobiki, and
S Noda, and
M Ueki
January 2008,
Neoplasma,
M Ueda, and
Y-C Hung, and
Y Terai, and
J Saito, and
O Nunobiki, and
S Noda, and
M Ueki
January 2002,
Journal of human genetics,
M Ueda, and
Y-C Hung, and
Y Terai, and
J Saito, and
O Nunobiki, and
S Noda, and
M Ueki
February 2002,
International journal of cancer,
M Ueda, and
Y-C Hung, and
Y Terai, and
J Saito, and
O Nunobiki, and
S Noda, and
M Ueki
April 2010,
Clinical biochemistry,
M Ueda, and
Y-C Hung, and
Y Terai, and
J Saito, and
O Nunobiki, and
S Noda, and
M Ueki
November 2004,
Cancer letters,
M Ueda, and
Y-C Hung, and
Y Terai, and
J Saito, and
O Nunobiki, and
S Noda, and
M Ueki
May 2006,
World journal of gastroenterology,
M Ueda, and
Y-C Hung, and
Y Terai, and
J Saito, and
O Nunobiki, and
S Noda, and
M Ueki
January 2008,
Neoplasma,
M Ueda, and
Y-C Hung, and
Y Terai, and
J Saito, and
O Nunobiki, and
S Noda, and
M Ueki
June 2016,
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine,
M Ueda, and
Y-C Hung, and
Y Terai, and
J Saito, and
O Nunobiki, and
S Noda, and
M Ueki
July 2009,
Oral oncology,
