-transparent.png){kind=logo}
Previous studies have shown that urea and acetamide traverse the erythrocyte membrane by way of facilitated diffusion. The nature of this selective pathway is unknown. The present studies investigate the effects of proteolytic enzymes and crosslinking agents on amide transport. Cleavage of the erythrocyte membrane surface by pronase or trypsin had no effect on urea and acetamide permeability or inhibition by phloretin. These findings suggest that the sialoglycopeptide segment of the sialoglycoproteins is not critical to urea and acetamide transport. In addition, extensive crosslinking of membrane proteins with glutaraldehyde had no effect on amide transport in the absence or presence of phloretin.
M A Kaplan, and
R M Hays, and
O O Blumenfeld
June 1981,
Biochimica et biophysica acta,
M A Kaplan, and
R M Hays, and
O O Blumenfeld
June 1979,
Nihon rinsho. Japanese journal of clinical medicine,
M A Kaplan, and
R M Hays, and
O O Blumenfeld
January 1987,
The Journal of membrane biology,
M A Kaplan, and
R M Hays, and
O O Blumenfeld
November 1971,
Biochemical and biophysical research communications,
M A Kaplan, and
R M Hays, and
O O Blumenfeld
January 1982,
Postepy biochemii,
M A Kaplan, and
R M Hays, and
O O Blumenfeld
August 1975,
The Journal of biological chemistry,
M A Kaplan, and
R M Hays, and
O O Blumenfeld
July 1970,
Biochemical and biophysical research communications,
M A Kaplan, and
R M Hays, and
O O Blumenfeld
January 1999,
Novartis Foundation symposium,
M A Kaplan, and
R M Hays, and
O O Blumenfeld
June 1980,
FEBS letters,
M A Kaplan, and
R M Hays, and
O O Blumenfeld
April 1972,
Biochimica et biophysica acta,
