BIOMAT Database Logo BIOMAT Database Logo

[Hepatic parenchymal changes after intraarterial administration of lipiodol: an animal experiment]. 1991

Y Akashi, and C Koreeda, and S Enomoto, and T Nishimura, and J Tateiwa, and T Mizuno, and K Inoue, and T Koreeda, and S K Ha-Kawa
Third Department of Internal Medicine, Kansai Medical University.

The effect of Lipiodol (LPD) on the hepatic parenchyma bearing VX2 tumor was investigated in 12 rabbits. In these rabbits Adriamycin (ADM) soluble Urografin and LPD were injected through the hepatic artery. As the control another 12 rabbits bearing VX2 tumor which were intraarterially injected with ADM solution in saline were used. Liver function tests revealed significantly higher values of serum transaminases in the LPD group than in the control group. Histologically in the LPD group, hepatocellular degeneration was observed and the severity was at its peak 3 days after injection whereas control animals preserved almost normal structure. The degeneration of the tumor-bearing lobe was more severe than that of the tumor-free lobe. This study showed the histologically and functionally demonstrable adverse effects of LPD.

UI MeSH Term Description Entries
D007269 Injections, Intra-Arterial Delivery of drugs into an artery. Injections, Intraarterial,Intra-Arterial Injections,Intraarterial Injections,Injection, Intra-Arterial,Injection, Intraarterial,Injections, Intra Arterial,Intra Arterial Injections,Intra-Arterial Injection,Intraarterial Injection
D007459 Iodized Oil A preparation of oil that contains covalently bound IODINE. It is commonly used as a RADIOCONTRAST AGENT and as a suspension medium for CHEMOTHERAPEUTIC AGENTS. Oil, Iodized,Iodized Oils,Iodolipol,Oils, Iodized
D008099 Liver A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances. Livers
D008114 Liver Neoplasms, Experimental Experimentally induced tumors of the LIVER. Hepatoma, Experimental,Hepatoma, Morris,Hepatoma, Novikoff,Experimental Hepatoma,Experimental Hepatomas,Experimental Liver Neoplasms,Hepatomas, Experimental,Neoplasms, Experimental Liver,Experimental Liver Neoplasm,Liver Neoplasm, Experimental,Morris Hepatoma,Novikoff Hepatoma
D008297 Male Males
D011817 Rabbits A burrowing plant-eating mammal with hind limbs that are longer than its fore limbs. It belongs to the family Leporidae of the order Lagomorpha, and in contrast to hares, possesses 22 instead of 24 pairs of chromosomes. Belgian Hare,New Zealand Rabbit,New Zealand Rabbits,New Zealand White Rabbit,Rabbit,Rabbit, Domestic,Chinchilla Rabbits,NZW Rabbits,New Zealand White Rabbits,Oryctolagus cuniculus,Chinchilla Rabbit,Domestic Rabbit,Domestic Rabbits,Hare, Belgian,NZW Rabbit,Rabbit, Chinchilla,Rabbit, NZW,Rabbit, New Zealand,Rabbits, Chinchilla,Rabbits, Domestic,Rabbits, NZW,Rabbits, New Zealand,Zealand Rabbit, New,Zealand Rabbits, New,cuniculus, Oryctolagus
D004317 Doxorubicin Antineoplastic antibiotic obtained from Streptomyces peucetius. It is a hydroxy derivative of DAUNORUBICIN. Adriamycin,Adriablastin,Adriablastine,Adriblastin,Adriblastina,Adriblastine,Adrimedac,DOXO-cell,Doxolem,Doxorubicin Hexal,Doxorubicin Hydrochloride,Doxorubicin NC,Doxorubicina Ferrer Farm,Doxorubicina Funk,Doxorubicina Tedec,Doxorubicine Baxter,Doxotec,Farmiblastina,Myocet,Onkodox,Ribodoxo,Rubex,Urokit Doxo-cell,DOXO cell,Hydrochloride, Doxorubicin,Urokit Doxo cell
D006499 Hepatic Artery A branch of the celiac artery that distributes to the stomach, pancreas, duodenum, liver, gallbladder, and greater omentum. Arteries, Hepatic,Artery, Hepatic,Hepatic Arteries
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia

Related Publications

Y Akashi, and C Koreeda, and S Enomoto, and T Nishimura, and J Tateiwa, and T Mizuno, and K Inoue, and T Koreeda, and S K Ha-Kawa
Hepatic parenchymal changes after intraarterial Y-90 therapy: CT findings.
April 1993, Radiology,
Y Akashi, and C Koreeda, and S Enomoto, and T Nishimura, and J Tateiwa, and T Mizuno, and K Inoue, and T Koreeda, and S K Ha-Kawa
Acalculous cholecystitis complicating hepatic intraarterial lipiodol: case report.
January 1989, Cardiovascular and interventional radiology,
Y Akashi, and C Koreeda, and S Enomoto, and T Nishimura, and J Tateiwa, and T Mizuno, and K Inoue, and T Koreeda, and S K Ha-Kawa
Disposition of epirubicin after intraarterial administration in Lipiodol to patients with hepatocellular carcinoma.
October 1996, Therapeutic drug monitoring,
Y Akashi, and C Koreeda, and S Enomoto, and T Nishimura, and J Tateiwa, and T Mizuno, and K Inoue, and T Koreeda, and S K Ha-Kawa
Hepatic intraarterial lipiodol: technique, semiologic patterns, and value for hepatic tumors.
January 1988, Gastrointestinal radiology,
Y Akashi, and C Koreeda, and S Enomoto, and T Nishimura, and J Tateiwa, and T Mizuno, and K Inoue, and T Koreeda, and S K Ha-Kawa
[Animal experiment studies after dextran administration].
June 1955, Der Anaesthesist,
Y Akashi, and C Koreeda, and S Enomoto, and T Nishimura, and J Tateiwa, and T Mizuno, and K Inoue, and T Koreeda, and S K Ha-Kawa
Dense parenchymal accumulation of Lipiodol after transarterial chemoembolization.
January 1992, Radiation medicine,
Y Akashi, and C Koreeda, and S Enomoto, and T Nishimura, and J Tateiwa, and T Mizuno, and K Inoue, and T Koreeda, and S K Ha-Kawa
[On vascular and parenchymal changes in the brain in embolism in animal experiment].
July 1961, Beitrage zur pathologischen Anatomie und zur allgemeinen Pathologie,
Y Akashi, and C Koreeda, and S Enomoto, and T Nishimura, and J Tateiwa, and T Mizuno, and K Inoue, and T Koreeda, and S K Ha-Kawa
[A new method of lipiodol hepatography using an intraarterial approach].
January 1972, Journal de radiologie, d'electrologie, et de medecine nucleaire,
Y Akashi, and C Koreeda, and S Enomoto, and T Nishimura, and J Tateiwa, and T Mizuno, and K Inoue, and T Koreeda, and S K Ha-Kawa
Adjuvant Intraarterial Lipiodol or ¹³¹I-Lipiodol After Curative Treatment of Hepatocellular Carcinoma: A Prospective Randomized Trial.
June 2014, Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
Y Akashi, and C Koreeda, and S Enomoto, and T Nishimura, and J Tateiwa, and T Mizuno, and K Inoue, and T Koreeda, and S K Ha-Kawa
[Animal experiment study on intracranial pressure, after ketamine administration].
February 1984, Der Anaesthesist,
Copied contents to your clipboard!