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This paper describes hemostatic changes in patients who had undergone aortic surgery under conditions of extracorporeal circulation. The changes in the hemostatic system are marked by the thrombophilic condition made up for activation ox blood fibrinolytic activity in the preoperative period. The basic amount of blood loss falls within the first 6 hours after operation. Prolonged hypothermic extracorporeal circulation and the high intraoperative blood loss (over 35 ml/kg bw) lead to an appreciable decrease in antithrombin III and protein C activity which results in activation of disseminated intravascular blood coagulation in the early postoperative period and ineffectiveness of heparin therapy. Secondary hyperfibrinolysis together with combined thrombocytopenia and platelet dysfunction are the basic causes of higher than usual bleeding in patients after aortic surgery under conditions of extracorporeal circulation.
M A Charnaia, and
Iu A Morozov, and
V G Gladysheva, and
E V Roĭtman, and
A M Isaeva, and
Iu V Belov, and
A V Goncharova
February 1967,
Kardiologiia,
M A Charnaia, and
Iu A Morozov, and
V G Gladysheva, and
E V Roĭtman, and
A M Isaeva, and
Iu V Belov, and
A V Goncharova
January 1978,
Polski przeglad chirurgiczny,
M A Charnaia, and
Iu A Morozov, and
V G Gladysheva, and
E V Roĭtman, and
A M Isaeva, and
Iu V Belov, and
A V Goncharova
January 1964,
Bibliotheca haematologica,
M A Charnaia, and
Iu A Morozov, and
V G Gladysheva, and
E V Roĭtman, and
A M Isaeva, and
Iu V Belov, and
A V Goncharova
July 1967,
Annales de chirurgie thoracique et cardio-vasculaire,
M A Charnaia, and
Iu A Morozov, and
V G Gladysheva, and
E V Roĭtman, and
A M Isaeva, and
Iu V Belov, and
A V Goncharova
February 1982,
La Nouvelle presse medicale,
M A Charnaia, and
Iu A Morozov, and
V G Gladysheva, and
E V Roĭtman, and
A M Isaeva, and
Iu V Belov, and
A V Goncharova
January 1970,
Grudnaia khirurgiia (Moscow, Russia),
M A Charnaia, and
Iu A Morozov, and
V G Gladysheva, and
E V Roĭtman, and
A M Isaeva, and
Iu V Belov, and
A V Goncharova
January 1972,
Grudnaia khirurgiia (Moscow, Russia),
M A Charnaia, and
Iu A Morozov, and
V G Gladysheva, and
E V Roĭtman, and
A M Isaeva, and
Iu V Belov, and
A V Goncharova
July 1963,
Annales de chirurgie thoracique et cardio-vasculaire,
M A Charnaia, and
Iu A Morozov, and
V G Gladysheva, and
E V Roĭtman, and
A M Isaeva, and
Iu V Belov, and
A V Goncharova
January 1978,
Bulletin europeen de physiopathologie respiratoire,
M A Charnaia, and
Iu A Morozov, and
V G Gladysheva, and
E V Roĭtman, and
A M Isaeva, and
Iu V Belov, and
A V Goncharova
January 1969,
Kardiologiia,
