BIOMAT Database Logo BIOMAT Database Logo

Acute and repeated exposure to social conflict in male golden hamsters: increases in plasma POMC-peptides and cortisol and decreases in plasma testosterone. 1991

K L Huhman, and T O Moore, and C F Ferris, and E H Mougey, and J L Meyerhoff
Department of Medical Neurosciences, Walter Reed Army Institute of Research, Washington, D.C. 20307-5100.

The purpose of the present study was to characterize the hormonal response of dominant and submissive male hamsters to acute and repeated exposure to social conflict. We found that submissive, but not dominant, males exhibited elevated plasma levels of adrenocorticotropin (ACTH), cortisol, and beta-endorphin (beta-EP) following one exposure to an agonistic encounter. After five exposures to a dominant opponent, submissive males showed smaller, but still significant, elevations in these plasma hormones. After nine exposures, submissive hamsters showed significant elevations only in plasma ACTH and beta-EP. Plasma testosterone was significantly suppressed in submissive males that fought nine times. We conclude that hamsters are a useful species with which to study the neuroendocrine correlates of social behavior.

UI MeSH Term Description Entries
D008297 Male Males
D008647 Mesocricetus A genus in the order Rodentia and family Cricetidae. One species, Mesocricetus auratus or golden hamster is widely used in biomedical research. Hamsters, Golden,Hamsters, Golden Syrian,Hamsters, Syrian,Mesocricetus auratus,Syrian Golden Hamster,Syrian Hamster,Golden Hamster,Golden Hamster, Syrian,Golden Hamsters,Golden Syrian Hamsters,Hamster, Golden,Hamster, Syrian,Hamster, Syrian Golden,Syrian Hamsters
D003220 Conflict, Psychological The internal individual struggle resulting from incompatible or opposing needs, drives, or external and internal demands. In group interactions, competitive or opposing action of incompatibles: antagonistic state or action (as of divergent ideas, interests, or persons). (from Merriam-Webster's Collegiate Dictionary, 10th ed) Conflict, Psychology,Psychological Conflict,Psychological Conflicts
D006224 Cricetinae A subfamily in the family MURIDAE, comprising the hamsters. Four of the more common genera are Cricetus, CRICETULUS; MESOCRICETUS; and PHODOPUS. Cricetus,Hamsters,Hamster
D006854 Hydrocortisone The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions. Cortef,Cortisol,Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11beta)-,11-Epicortisol,Cortifair,Cortril,Epicortisol,Hydrocortisone, (11 alpha)-Isomer,Hydrocortisone, (9 beta,10 alpha,11 alpha)-Isomer,11 Epicortisol
D000324 Adrenocorticotropic Hormone An anterior pituitary hormone that stimulates the ADRENAL CORTEX and its production of CORTICOSTEROIDS. ACTH is a 39-amino acid polypeptide of which the N-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Upon further tissue-specific processing, ACTH can yield ALPHA-MSH and corticotrophin-like intermediate lobe peptide (CLIP). ACTH,Adrenocorticotropin,Corticotropin,1-39 ACTH,ACTH (1-39),Adrenocorticotrophic Hormone,Corticotrophin,Corticotrophin (1-39),Corticotropin (1-39),Hormone, Adrenocorticotrophic,Hormone, Adrenocorticotropic
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001522 Behavior, Animal The observable response an animal makes to any situation. Autotomy Animal,Animal Behavior,Animal Behaviors
D001615 beta-Endorphin A 31-amino acid peptide that is the C-terminal fragment of BETA-LIPOTROPIN. It acts on OPIOID RECEPTORS and is an analgesic. Its first four amino acids at the N-terminal are identical to the tetrapeptide sequence of METHIONINE ENKEPHALIN and LEUCINE ENKEPHALIN. Endorphin, beta,beta-Endorphin (1-31),beta Endorphin
D012930 Social Dominance Social structure of a group as it relates to the relative social rank of dominance status of its members. (APA, Thesaurus of Psychological Index Terms, 8th ed.) Dominance Hierarchy,Dominance, Social,Dominance Hierarchies,Hierarchy, Dominance

Related Publications

K L Huhman, and T O Moore, and C F Ferris, and E H Mougey, and J L Meyerhoff
Effects of social conflict on POMC-derived peptides and glucocorticoids in male golden hamsters.
May 1990, Physiology & behavior,
K L Huhman, and T O Moore, and C F Ferris, and E H Mougey, and J L Meyerhoff
Repeated exposure to social stress alters the development of agonistic behavior in male golden hamsters.
January 2003, Hormones and behavior,
K L Huhman, and T O Moore, and C F Ferris, and E H Mougey, and J L Meyerhoff
Psychologic stress increases plasma levels of prolactin, cortisol, and POMC-derived peptides in man.
January 1988, Psychosomatic medicine,
K L Huhman, and T O Moore, and C F Ferris, and E H Mougey, and J L Meyerhoff
Testosterone reduces olfactory neophobia in male golden hamsters.
June 1981, Physiology & behavior,
K L Huhman, and T O Moore, and C F Ferris, and E H Mougey, and J L Meyerhoff
Repeated exposure to acetaldehyde vapor. Studies in Syrian golden hamsters.
September 1975, Archives of environmental health,
K L Huhman, and T O Moore, and C F Ferris, and E H Mougey, and J L Meyerhoff
Repeated exposure to butenolide vapour: subacute study in Syrian golden hamsters.
December 1979, Toxicology,
K L Huhman, and T O Moore, and C F Ferris, and E H Mougey, and J L Meyerhoff
Voluntary exercise increases gonadotropin secretion in male Golden hamsters.
July 1995, The American journal of physiology,
K L Huhman, and T O Moore, and C F Ferris, and E H Mougey, and J L Meyerhoff
Blinding increases territorial aggression in male Syrian golden hamsters.
May 1976, Behavioral biology,
K L Huhman, and T O Moore, and C F Ferris, and E H Mougey, and J L Meyerhoff
Behavioural and neuroendocrine adaptations to repeated stress during puberty in male golden hamsters.
September 2004, Journal of neuroendocrinology,
K L Huhman, and T O Moore, and C F Ferris, and E H Mougey, and J L Meyerhoff
Repeated exposure to furfural vapour: 13-week study in Syrian golden hamsters.
June 1979, Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe B: Hygiene, Betriebshygiene, praventive Medizin,
Copied contents to your clipboard!