BIOMAT Database Logo BIOMAT Database Logo

Comparison of morbidity and function after colectomy with ileorectal anastomosis or restorative proctocolectomy for familial adenomatous polyposis. 1991

M V Madden, and K F Neale, and R J Nicholls, and J C Landgrebe, and P D Chapman, and H J Bussey, and J P Thomson
Department of Surgery, St. Mark's Hospital, London, UK.

Restorative proctocolectomy with an ileal reservoir (RPC) should prevent colorectal cancer in patients with familial adenomatous polyposis. Until this is confirmed its role compared with total colectomy and ileorectal anastomosis (IRA) will depend on the relative morbidity and postoperative bowel function after the two procedures. This was analysed in 99 patients (37 RPC, 62 IRA) operated on between 1977 and 1989. Morbidity was greater after RPC with subsequent ileostomy closure (median hospital stay, 24 versus 11 days; complications, 60 versus 21 per cent; reoperation, 29 versus 3 per cent; return to normal activity; 31 versus 14 weeks). There was little difference in bowel function; after IRA median frequency was 3/24 h and urgency (unable to wait 15 min) occurred in 50 per cent, compared with 4.5/24h and 17 per cent after RPC. Night evacuation occurred in 10 and 43 per cent respectively. IRA was performed in younger patients (median 19 versus 31 years) who had fewer bowel motions before operation (2 versus 5/24 h). The greater morbidity of RPC suggests that it should be restricted to patients at higher risk of developing later rectal cancer, including those unavailable for follow-up and those with large or confluent rectal polyps or with curable colon cancer at the initial colectomy.

UI MeSH Term Description Entries
D007081 Ileostomy Surgical creation of an external opening into the ILEUM for fecal diversion or drainage. This replacement for the RECTUM is usually created in patients with severe INFLAMMATORY BOWEL DISEASES. Loop (continent) or tube (incontinent) procedures are most often employed. Loop Ileostomy,Tube Ileostomy,Continent Ileostomy,Incontinent Ileostomy,Continent Ileostomies,Ileostomies,Ileostomies, Continent,Ileostomies, Incontinent,Ileostomies, Loop,Ileostomies, Tube,Ileostomy, Continent,Ileostomy, Incontinent,Ileostomy, Loop,Ileostomy, Tube,Incontinent Ileostomies,Loop Ileostomies,Tube Ileostomies
D007082 Ileum The distal and narrowest portion of the SMALL INTESTINE, between the JEJUNUM and the ILEOCECAL VALVE of the LARGE INTESTINE.
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011125 Adenomatous Polyposis Coli A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood. Polyposis Coli, Familial,Polyposis Syndrome, Familial,Adenomatous Polyposis Coli, Familial,Adenomatous Polyposis of the Colon,Familial Adenomatous Polyposis,Familial Adenomatous Polyposis Coli,Familial Adenomatous Polyposis of the Colon,Familial Intestinal Polyposis,Familial Multiple Polyposi,Familial Multiple Polyposis,Familial Multiple Polyposis Syndrome,Familial Polyposis Coli,Familial Polyposis Syndrome,Familial Polyposis of the Colon,Hereditary Polyposis Coli,Myh-Associated Polyposis,Polyposis Coli,Polyposis, Adenomatous Intestinal,Adenomatous Intestinal Polyposes,Adenomatous Intestinal Polyposis,Adenomatous Polyposes, Familial,Adenomatous Polyposis Colus,Adenomatous Polyposis, Familial,Coli, Adenomatous Polyposis,Coli, Familial Polyposis,Coli, Hereditary Polyposis,Coli, Polyposis,Colus, Adenomatous Polyposis,Colus, Familial Polyposis,Colus, Hereditary Polyposis,Colus, Polyposis,Familial Adenomatous Polyposes,Familial Intestinal Polyposes,Familial Multiple Polyposes,Familial Multiple Polyposus,Familial Polyposis Colus,Familial Polyposis Syndromes,Hereditary Polyposis Colus,Intestinal Polyposes, Familial,Intestinal Polyposis, Adenomatous,Intestinal Polyposis, Familial,Multiple Polyposes, Familial,Multiple Polyposi, Familial,Multiple Polyposis, Familial,Multiple Polyposus, Familial,Myh Associated Polyposis,Myh-Associated Polyposes,Polyposes, Familial Adenomatous,Polyposes, Familial Multiple,Polyposes, Myh-Associated,Polyposi, Familial Multiple,Polyposis Coli, Adenomatous,Polyposis Coli, Hereditary,Polyposis Colus,Polyposis Colus, Adenomatous,Polyposis Colus, Familial,Polyposis Colus, Hereditary,Polyposis, Familial Adenomatous,Polyposis, Familial Multiple,Polyposis, Myh-Associated,Polyposus, Familial Multiple
D011183 Postoperative Complications Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery. Complication, Postoperative,Complications, Postoperative,Postoperative Complication
D011379 Prognosis A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations. Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D012007 Rectum The distal segment of the LARGE INTESTINE, between the SIGMOID COLON and the ANAL CANAL. Rectums
D012086 Reoperation A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery. Revision, Joint,Revision, Surgical,Surgery, Repeat,Surgical Revision,Repeat Surgery,Revision Surgery,Joint Revision,Revision Surgeries,Surgery, Revision
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children

Related Publications

M V Madden, and K F Neale, and R J Nicholls, and J C Landgrebe, and P D Chapman, and H J Bussey, and J P Thomson
Morbidity and function after colectomy with ileorectal anastomosis or restorative proctocolectomy for familial adenomatous polyposis.
January 1992, The British journal of surgery,
M V Madden, and K F Neale, and R J Nicholls, and J C Landgrebe, and P D Chapman, and H J Bussey, and J P Thomson
Colectomy with ileorectal anastomosis or restorative proctocolectomy for familial adenomatous polyposis.
July 1992, The British journal of surgery,
M V Madden, and K F Neale, and R J Nicholls, and J C Landgrebe, and P D Chapman, and H J Bussey, and J P Thomson
Colectomy and ileorectal anastomosis or restorative proctocolectomy for familial adenomatous polyposis.
January 1999, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland,
M V Madden, and K F Neale, and R J Nicholls, and J C Landgrebe, and P D Chapman, and H J Bussey, and J P Thomson
Quality of life after total colectomy with ileorectal anastomosis or proctocolectomy and ileal pouch-anal anastomosis for familial adenomatous polyposis.
May 2000, The British journal of surgery,
M V Madden, and K F Neale, and R J Nicholls, and J C Landgrebe, and P D Chapman, and H J Bussey, and J P Thomson
Comparison of proctocolectomy and ileal pouch-anal anastomosis to colectomy and ileorectal anastomosis in familial adenomatous polyposis.
June 2015, Familial cancer,
M V Madden, and K F Neale, and R J Nicholls, and J C Landgrebe, and P D Chapman, and H J Bussey, and J P Thomson
Sulindac therapy for familial adenomatous polyposis after colectomy and ileorectal anastomosis.
January 1994, Annales chirurgiae et gynaecologiae,
M V Madden, and K F Neale, and R J Nicholls, and J C Landgrebe, and P D Chapman, and H J Bussey, and J P Thomson
Life expectancy after colectomy and ileorectal anastomosis for familial adenomatous polyposis.
November 1993, Diseases of the colon and rectum,
M V Madden, and K F Neale, and R J Nicholls, and J C Landgrebe, and P D Chapman, and H J Bussey, and J P Thomson
Laparoscopic colectomy and restorative proctocolectomy for familial adenomatous polyposis.
June 2011, Surgical endoscopy,
M V Madden, and K F Neale, and R J Nicholls, and J C Landgrebe, and P D Chapman, and H J Bussey, and J P Thomson
Functional outcome after colectomy and ileorectal anastomosis compared with proctocolectomy and ileal pouch-anal anastomosis in familial adenomatous polyposis.
November 1999, Annals of surgery,
M V Madden, and K F Neale, and R J Nicholls, and J C Landgrebe, and P D Chapman, and H J Bussey, and J P Thomson
Surgical treatment of familial adenomatous polyposis: ileorectal anastomosis or restorative proctolectomy?
January 2009, Arquivos de gastroenterologia,
Copied contents to your clipboard!