[Molecular mechanisms underlying renal hypertension]. 2006

Tsuneo Takenaka, and Yoshihiko Kanno, and Hirokazu Okada, and Hidetomo Nakamoto, and Hiromichi Suzuki
Department of Nephrology, Saitama Medical College.

UI MeSH Term Description Entries
D006977 Hypertension, Renal Persistent high BLOOD PRESSURE due to KIDNEY DISEASES, such as those involving the renal parenchyma, the renal vasculature, or tumors that secrete RENIN. Hypertensions, Renal,Renal Hypertension,Renal Hypertensions
D006994 Hypoaldosteronism A congenital or acquired condition of insufficient production of ALDOSTERONE by the ADRENAL CORTEX leading to diminished aldosterone-mediated synthesis of Na(+)-K(+)-EXCHANGING ATPASE in renal tubular cells. Clinical symptoms include HYPERKALEMIA, sodium-wasting, HYPOTENSION, and sometimes metabolic ACIDOSIS. Acidosis, Renal Tubular Type IV,Hypoaldosteronism, Hyporeninemic,Renal Tubular Acidosis, Type IV,Type IV Renal Tubular Acidosis,Hyporeninemic Hypoaldosteronism
D007008 Hypokalemia Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed) Hypopotassemia,Hypokalemias,Hypopotassemias
D007690 Polycystic Kidney Diseases Hereditary diseases that are characterized by the progressive expansion of a large number of tightly packed CYSTS within the KIDNEYS. They include diseases with autosomal dominant and autosomal recessive inheritance. Kidney, Polycystic,Polycystic Kidney,Polycystic Kidney Disease,Polycystic Kidneys,Polycystic Renal Disease,Disease, Polycystic Kidney,Disease, Polycystic Renal,Diseases, Polycystic Kidney,Diseases, Polycystic Renal,Kidney Disease, Polycystic,Kidney Diseases, Polycystic,Kidneys, Polycystic,Polycystic Renal Diseases,Renal Disease, Polycystic,Renal Diseases, Polycystic
D009154 Mutation Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations. Mutations
D011507 Proteinuria The presence of proteins in the urine, an indicator of KIDNEY DISEASES. Proteinurias
D011546 Pseudohypoaldosteronism A heterogeneous group of disorders characterized by renal electrolyte transport dysfunctions. Congenital forms are rare autosomal disorders characterized by neonatal hypertension, HYPERKALEMIA, increased RENIN activity and ALDOSTERONE concentration. The Type I features HYPERKALEMIA with sodium wasting; Type II, HYPERKALEMIA without sodium wasting. Pseudohypoaldosteronism can be the result of a defective renal electrolyte transport protein or acquired after KIDNEY TRANSPLANTATION. Gordon Hyperkalemia-Hypertension Syndrome,Hyperpotassemia and Hypertension, Familial,Hypertensive Hyperkalemia, Familial,Pseudohypoaldosteronism Type 1,Pseudohypoaldosteronism Type 1, Autosomal Recessive,Pseudohypoaldosteronism, Type I,Pseudohypoaldosteronism, Type I, Autosomal Dominant,Pseudohypoaldosteronism, Type I, Autosomal Recessive,Pseudohypoaldosteronism, Type II,Familial Hyperpotassemia and Hypertension,Familial Hypertensive Hyperkalemia,Pseudohypoaldosteronism Type 1, Autosomal Dominant,Pseudohypoaldosteronism Type 2,Pseudohypoaldosteronism Type I,Pseudohypoaldosteronism Type II,Familial Hypertensive Hyperkalemias,Gordon Hyperkalemia Hypertension Syndrome,Hyperkalemia, Familial Hypertensive,Hyperkalemia-Hypertension Syndrome, Gordon,Hyperkalemias, Familial Hypertensive,Hypertensive Hyperkalemias, Familial,Pseudohypoaldosteronism Type 1s,Pseudohypoaldosteronism Type 2s,Pseudohypoaldosteronism Type IIs,Pseudohypoaldosteronism Type Is,Pseudohypoaldosteronisms,Pseudohypoaldosteronisms, Type I,Pseudohypoaldosteronisms, Type II,Syndrome, Gordon Hyperkalemia-Hypertension,Type 1, Pseudohypoaldosteronism,Type I Pseudohypoaldosteronism,Type I, Pseudohypoaldosteronism,Type II Pseudohypoaldosteronism,Type II Pseudohypoaldosteronisms,Type II, Pseudohypoaldosteronism,Type IIs, Pseudohypoaldosteronism,Type Is, Pseudohypoaldosteronism
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001161 Arteriosclerosis Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries. Arterioscleroses
D013577 Syndrome A characteristic symptom complex. Symptom Cluster,Cluster, Symptom,Clusters, Symptom,Symptom Clusters,Syndromes

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