OBJECTIVE To determine potential patterns that cause males and females to tear the anterior cruciate ligament (ACL) while playing basketball or soccer. METHODS We reviewed data submitted to the National Collegiate Athletic Association Injury Surveillance System over the last 10 years, as well as profile data collected from collegiate certified athletic trainers. METHODS College athletes involved in basketball or soccer. METHODS Historical information was collected on those athletes involved in the National Collegiate Athletic Association Injury Surveillance System. Athletes involved in the profiling study underwent physical measurements related to flexibility, as well as a more detailed history relating to the ACL tear. RESULTS College-age women involved in basketball or soccer tear their ACLs at significantly higher rates than college-age men involved in the same sports. No distinct physical or historical measurements could be attributed to this different rate of injury. CONCLUSIONS Although the higher rate at which women compared with men tear their ACLs has persisted over the last 10 years, this increased incidence is not clearly attributable to any physical or historical measurements that were monitored.