Biomaterial Database

Uncommon, exceptional and atypical: a case of frontal lobe epilepsy due to cortical dysplasia. 2006

Arthur C Grant, and Richard B Kim

Department of Neurology, New York University School of Medicine, USA. arthur.grant@med.nyu.edu

We report a case of frontal lobe epilepsy due to focal cortical dysplasia that included three independent unusual features. The patient, a 45-year-old, right-handed woman, had her first seizure at age 29, well into adulthood. Seizures had been easily controlled with medication for 15 years, then without provocation they became medically intractable during a single, identifiable day. Resection of the dysplastic tissue in the posterior dorsolateral right frontal cortex rendered the patient seizure-free, but produced a significant, non-fluent, Broca type, crossed aphasia. In addition, the seizure semiology was striking and remarkable, a common finding in frontal lobe epilepsy. [Published with video sequences].

UI	MeSH Term	Description	Entries
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D002540	Cerebral Cortex	The thin layer of GRAY MATTER on the surface of the CEREBRAL HEMISPHERES that develops from the TELENCEPHALON and folds into gyri and sulci. It reaches its highest development in humans and is responsible for intellectual faculties and higher mental functions.	Allocortex,Archipallium,Cortex Cerebri,Cortical Plate,Paleocortex,Periallocortex,Allocortices,Archipalliums,Cerebral Cortices,Cortex Cerebrus,Cortex, Cerebral,Cortical Plates,Paleocortices,Periallocortices,Plate, Cortical
D005260	Female		Females
D005625	Frontal Lobe	The part of the cerebral hemisphere anterior to the central sulcus, and anterior and superior to the lateral sulcus.	Brodmann Area 8,Brodmann's Area 8,Frontal Cortex,Frontal Eye Fields,Lobus Frontalis,Supplementary Eye Field,Area 8, Brodmann,Area 8, Brodmann's,Brodmanns Area 8,Cortex, Frontal,Eye Field, Frontal,Eye Field, Supplementary,Eye Fields, Frontal,Frontal Cortices,Frontal Eye Field,Frontal Lobes,Lobe, Frontal,Supplementary Eye Fields
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001037	Aphasia	A cognitive disorder marked by an impaired ability to comprehend or express language in its written or spoken form. This condition is caused by diseases which affect the language areas of the dominant hemisphere. Clinical features are used to classify the various subtypes of this condition. General categories include receptive, expressive, and mixed forms of aphasia.	Aphasia, Acquired,Dysphasia,Word Deafness,Alogia,Anepia,Aphasia, Ageusic,Aphasia, Auditory Discriminatory,Aphasia, Commisural,Aphasia, Functional,Aphasia, Global,Aphasia, Graphomotor,Aphasia, Intellectual,Aphasia, Mixed,Aphasia, Post-Ictal,Aphasia, Post-Traumatic,Aphasia, Progressive,Aphasia, Semantic,Aphasia, Syntactical,Dejerine-Lichtheim Phenomenon,Dysphasia, Global,Lichtheim's Sign,Logagnosia,Logamnesia,Logasthenia,Acquired Aphasia,Ageusic Aphasia,Ageusic Aphasias,Alogias,Anepias,Aphasia, Post Ictal,Aphasia, Post Traumatic,Aphasias, Commisural,Auditory Discriminatory Aphasia,Auditory Discriminatory Aphasias,Commisural Aphasia,Commisural Aphasias,Deafness, Word,Dejerine Lichtheim Phenomenon,Discriminatory Aphasia, Auditory,Discriminatory Aphasias, Auditory,Functional Aphasia,Functional Aphasias,Global Aphasia,Global Aphasias,Global Dysphasia,Global Dysphasias,Graphomotor Aphasia,Graphomotor Aphasias,Intellectual Aphasia,Intellectual Aphasias,Lichtheim Sign,Lichtheims Sign,Logagnosias,Logamnesias,Logasthenias,Mixed Aphasia,Mixed Aphasias,Phenomenon, Dejerine-Lichtheim,Post-Ictal Aphasia,Post-Ictal Aphasias,Post-Traumatic Aphasia,Post-Traumatic Aphasias,Progressive Aphasia,Progressive Aphasias,Semantic Aphasia,Semantic Aphasias,Sign, Lichtheim's,Syntactical Aphasia,Syntactical Aphasias
D014741	Video Recording	The storing or preserving of video signals to be played back later via a transmitter or receiver.	Audiovisual Recording,Videorecording,Audiovisual Recordings,Recording, Audiovisual,Recording, Video,Recordings, Audiovisual,Recordings, Video,Video Recordings,Videorecordings
D017034	Epilepsy, Frontal Lobe	A localization-related (focal) form of epilepsy characterized by seizures which arise in the FRONTAL LOBE.	Frontal Epilepsy, Benign, Childhood,Frontal Lobe Epilepsy,Benign Frontal Childhood Epilepsy,Childhood Benign Frontal Epilepsy,Epilepsy, Anterior Fronto-Polar,Epilepsy, Benign Frontal, Childhood,Epilepsy, Cingulate,Epilepsy, Opercular,Epilepsy, Orbito-Frontal,Epilepsy, Supplementary Motor,Anterior Fronto-Polar Epilepsies,Anterior Fronto-Polar Epilepsy,Cingulate Epilepsies,Cingulate Epilepsy,Epilepsies, Anterior Fronto-Polar,Epilepsies, Cingulate,Epilepsies, Orbito-Frontal,Epilepsies, Supplementary Motor,Epilepsy, Anterior Fronto Polar,Epilepsy, Orbito Frontal,Frontal Lobe Epilepsies,Opercular Epilepsies,Opercular Epilepsy,Orbito-Frontal Epilepsies,Orbito-Frontal Epilepsy,Supplementary Motor Epilepsies,Supplementary Motor Epilepsy