BIOMAT Database Logo BIOMAT Database Logo

NK-2 receptor agonists and antagonists. 1991

C A Maggi, and R Patacchini, and M Astolfi, and P Rovero, and S Giuliani, and A Giachetti
Department of Pharmacology, A. Menarini Pharmaceuticals, Florence, Italy.

UI MeSH Term Description Entries
D008969 Molecular Sequence Data Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories. Sequence Data, Molecular,Molecular Sequencing Data,Data, Molecular Sequence,Data, Molecular Sequencing,Sequencing Data, Molecular
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000595 Amino Acid Sequence The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION. Protein Structure, Primary,Amino Acid Sequences,Sequence, Amino Acid,Sequences, Amino Acid,Primary Protein Structure,Primary Protein Structures,Protein Structures, Primary,Structure, Primary Protein,Structures, Primary Protein
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D013329 Structure-Activity Relationship The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups. Relationship, Structure-Activity,Relationships, Structure-Activity,Structure Activity Relationship,Structure-Activity Relationships
D015288 Neurokinin A A mammalian neuropeptide of 10 amino acids that belongs to the tachykinin family. It is similar in structure and action to SUBSTANCE P and NEUROKININ B with the ability to excite neurons, dilate blood vessels, and contract smooth muscles, such as those in the BRONCHI. Substance K,Neurokinin alpha,Neuromedin L
D015320 Tachykinins A family of biologically active peptides sharing a common conserved C-terminal sequence, -Phe-X-Gly-Leu-Met-NH2, where X is either an aromatic or a branched aliphatic amino acid. Members of this family have been found in mammals, amphibians, and mollusks. Tachykinins have diverse pharmacological actions in the central nervous system and the cardiovascular, genitourinary, respiratory, and gastrointestinal systems, as well as in glandular tissues. This diversity of activity is due to the existence of three or more subtypes of tachykinin receptors. Tachykinin
D017981 Receptors, Neurotransmitter Cell surface receptors that bind signalling molecules released by neurons and convert these signals into intracellular changes influencing the behavior of cells. Neurotransmitter is used here in its most general sense, including not only messengers that act to regulate ion channels, but also those which act on second messenger systems and those which may act at a distance from their release sites. Included are receptors for neuromodulators, neuroregulators, neuromediators, and neurohumors, whether or not located at synapses. Neurohumor Receptors,Neuromediator Receptors,Neuromodulator Receptors,Neuroregulator Receptors,Receptors, Neurohumor,Receptors, Synaptic,Synaptic Receptor,Synaptic Receptors,Neuromediator Receptor,Neuromodulator Receptor,Neuroregulator Receptor,Neurotransmitter Receptor,Receptors, Neuromediators,Receptors, Neuromodulators,Receptors, Neuroregulators,Receptors, Neurotransmitters,Neuromediators Receptors,Neuromodulators Receptors,Neuroregulators Receptors,Neurotransmitter Receptors,Neurotransmitters Receptors,Receptor, Neuromediator,Receptor, Neuromodulator,Receptor, Neuroregulator,Receptor, Neurotransmitter,Receptor, Synaptic,Receptors, Neuromediator,Receptors, Neuromodulator,Receptors, Neuroregulator
D018039 Receptors, Tachykinin Cell surface proteins that bind TACHYKININS with high affinity and trigger intracellular changes influencing the behavior of cells. Three classes of tachykinin receptors have been characterized, the NK-1; NK-2; and NK-3; which prefer, respectively, SUBSTANCE P; NEUROKININ A; and NEUROKININ B. Tachykinin Receptors,Receptors, Tachykinins,Tachykinin Receptor,Receptor, Tachykinin,Tachykinins Receptors

Related Publications

C A Maggi, and R Patacchini, and M Astolfi, and P Rovero, and S Giuliani, and A Giachetti
Protease-activated receptor-2 antagonists and agonists.
March 2003, Current medicinal chemistry. Cardiovascular and hematological agents,
C A Maggi, and R Patacchini, and M Astolfi, and P Rovero, and S Giuliani, and A Giachetti
Biphenyl derivatives as novel dual NK(1)/NK(2)-receptor antagonists.
August 2002, Bioorganic & medicinal chemistry letters,
C A Maggi, and R Patacchini, and M Astolfi, and P Rovero, and S Giuliani, and A Giachetti
Small molecule antagonists of the tachykinin NK 2 receptor.
March 2004, Mini reviews in medicinal chemistry,
C A Maggi, and R Patacchini, and M Astolfi, and P Rovero, and S Giuliani, and A Giachetti
Dopamine receptor agonists and antagonists.
January 1990, Proceedings of the Western Pharmacology Society,
C A Maggi, and R Patacchini, and M Astolfi, and P Rovero, and S Giuliani, and A Giachetti
Cannabinoid receptor 2 (CB2) agonists and antagonists: a patent update.
July 2016, Expert opinion on therapeutic patents,
C A Maggi, and R Patacchini, and M Astolfi, and P Rovero, and S Giuliani, and A Giachetti
Novel agonists and antagonists for human protease activated receptor 2.
October 2010, Journal of medicinal chemistry,
C A Maggi, and R Patacchini, and M Astolfi, and P Rovero, and S Giuliani, and A Giachetti
A2A adenosine receptor agonists, antagonists, inverse agonists and partial agonists.
January 2023, International review of neurobiology,
C A Maggi, and R Patacchini, and M Astolfi, and P Rovero, and S Giuliani, and A Giachetti
Alpha 2 agonists and antagonists.
May 1999, The Veterinary clinics of North America. Small animal practice,
C A Maggi, and R Patacchini, and M Astolfi, and P Rovero, and S Giuliani, and A Giachetti
Novel bifunctional peptides as opioid agonists and NK-1 antagonists.
January 2009, Advances in experimental medicine and biology,
C A Maggi, and R Patacchini, and M Astolfi, and P Rovero, and S Giuliani, and A Giachetti
MCH receptor peptide agonists and antagonists.
November 2009, Peptides,
Copied contents to your clipboard!