BIOMAT Database Logo BIOMAT Database Logo

Virological response to highly active antiretroviral therapy is unaffected by antituberculosis therapy. 2006

Ronan A M Breen, and R F Miller, and T Gorsuch, and C J Smith, and J Ainsworth, and J Ballinger, and L Swaden, and I Cropley, and M A Johnson, and M C I Lipman
Department of HIV Medicine, Royal Free Hospital, and Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, United Kingdom. r.breen@medsch.ucl.ac.uk

We compared 156 human immunodeficiency virus (HIV)-infected patients who had tuberculosis with control populations of similar size. Of 111 patients with HIV infection and tuberculosis who received highly active antiretroviral therapy (HAART) and therapy for tuberculosis concurrently, 92 (83%) achieved or maintained virus loads of <50 copies/mL, and 99 (89%) achieved or maintained a >or=2 log10 reduction in virus load after 6 months. Virological response and changes in CD4 cell count were equivalent to those in 111 matched HIV-infected subjects without tuberculosis starting HAART. Tuberculosis recurrence rates were similar to those found in an HIV-uninfected population of 156 subjects (3% and 1%, respectively). Treatment for HIV and tuberculosis does not compromise outcomes for either disease.

UI MeSH Term Description Entries
D008131 London The capital of the United Kingdom. It is located in England.
D008297 Male Males
D008499 Medical Records Recording of pertinent information concerning patient's illness or illnesses. Health Diaries,Medical Transcription,Records, Medical,Transcription, Medical,Diaries, Health,Diary, Health,Health Diary,Medical Record,Medical Transcriptions,Record, Medical,Transcriptions, Medical
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D012008 Recurrence The return of a sign, symptom, or disease after a remission. Recrudescence,Relapse,Recrudescences,Recurrences,Relapses
D004359 Drug Therapy, Combination Therapy with two or more separate preparations given for a combined effect. Combination Chemotherapy,Polychemotherapy,Chemotherapy, Combination,Combination Drug Therapy,Drug Polytherapy,Therapy, Combination Drug,Chemotherapies, Combination,Combination Chemotherapies,Combination Drug Therapies,Drug Polytherapies,Drug Therapies, Combination,Polychemotherapies,Polytherapies, Drug,Polytherapy, Drug,Therapies, Combination Drug
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly

Related Publications

Ronan A M Breen, and R F Miller, and T Gorsuch, and C J Smith, and J Ainsworth, and J Ballinger, and L Swaden, and I Cropley, and M A Johnson, and M C I Lipman
Impact of antituberculosis treatment on virological response to highly active antiretroviral therapy: implications for resource-limited settings?
November 2006, The Journal of infectious diseases,
Ronan A M Breen, and R F Miller, and T Gorsuch, and C J Smith, and J Ainsworth, and J Ballinger, and L Swaden, and I Cropley, and M A Johnson, and M C I Lipman
Factors associated with incomplete virological response to highly active antiretroviral therapy.
February 2000, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America,
Ronan A M Breen, and R F Miller, and T Gorsuch, and C J Smith, and J Ainsworth, and J Ballinger, and L Swaden, and I Cropley, and M A Johnson, and M C I Lipman
Virological rebound after suppression on highly active antiretroviral therapy.
August 2003, AIDS (London, England),
Ronan A M Breen, and R F Miller, and T Gorsuch, and C J Smith, and J Ainsworth, and J Ballinger, and L Swaden, and I Cropley, and M A Johnson, and M C I Lipman
Initial virological and immunologic response to highly active antiretroviral therapy predicts long-term clinical outcome.
August 2001, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America,
Ronan A M Breen, and R F Miller, and T Gorsuch, and C J Smith, and J Ainsworth, and J Ballinger, and L Swaden, and I Cropley, and M A Johnson, and M C I Lipman
Immunological response to hepatitis B vaccination in patients with AIDS and virological response to highly active antiretroviral therapy.
January 2008, Scandinavian journal of infectious diseases,
Ronan A M Breen, and R F Miller, and T Gorsuch, and C J Smith, and J Ainsworth, and J Ballinger, and L Swaden, and I Cropley, and M A Johnson, and M C I Lipman
Long-term virological response to multiple sequential regimens of highly active antiretroviral therapy for HIV infection.
April 2004, Antiviral therapy,
Ronan A M Breen, and R F Miller, and T Gorsuch, and C J Smith, and J Ainsworth, and J Ballinger, and L Swaden, and I Cropley, and M A Johnson, and M C I Lipman
Effect of genotypic resistance on the virological response to highly active antiretroviral therapy in cerebrospinal fluid.
March 2001, AIDS research and human retroviruses,
Ronan A M Breen, and R F Miller, and T Gorsuch, and C J Smith, and J Ainsworth, and J Ballinger, and L Swaden, and I Cropley, and M A Johnson, and M C I Lipman
Predictors of response to highly active antiretroviral therapy.
August 2006, The AIDS reader,
Ronan A M Breen, and R F Miller, and T Gorsuch, and C J Smith, and J Ainsworth, and J Ballinger, and L Swaden, and I Cropley, and M A Johnson, and M C I Lipman
Superior virological response to boosted protease inhibitor-based highly active antiretroviral therapy in an observational treatment programme.
March 2007, HIV medicine,
Ronan A M Breen, and R F Miller, and T Gorsuch, and C J Smith, and J Ainsworth, and J Ballinger, and L Swaden, and I Cropley, and M A Johnson, and M C I Lipman
Immune correlates of virological response in HIV-positive patients after highly active antiretroviral therapy (HAART).
January 2004, Viral immunology,
Copied contents to your clipboard!