Acutely decompensated heart failure: characteristics of hospitalized patients and opportunities to improve their care. 2006

Pedro Moraes Sarmento, and Cândida Fonseca, and Filipa Marques, and Fátima Ceia, and Ana Aleixo
Serviço Universitário de Medicina, Hospital de S. Francisco Xavier, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisboa, Portugal. pmsarmento@netcabo.pt

Heart failure (HF) remains a major public health problem in western countries, despite the enormous progress in its diagnosis and treatment. Acute and chronic decompensated HF are leading medical causes of hospitalization among people aged over 65 years in European countries, the USA, Australia and New Zealand. However, there have been few studies on acute and chronic decompensated HF and the European Society of Cardiology (ESC) guidelines on this subject have only just been published. OBJECTIVE To evaluate the overall prevalence of hospitalization due to HF according to its subtypes, comorbidities, and decompensating factors, in the Medical Department of a central teaching hospital in an urban area. METHODS We performed a retrospective observational study of patients admitted consecutively to the Medical Department via the emergency room between January and June 2001. Discharge casenotes on 1038 admissions were reviewed. Those with a diagnosis of HF or cardiovascular conditions associated with or precursors of HF were analyzed. Cases with a final diagnosis of HF according to the criteria of the ESC guidelines were included in the study. We evaluated the overall prevalence of HF and subtypes of cardiac dysfunction, etiological risk factors, patients' demographic characteristics, decompensating factors, comorbidity, mean length of hospital stay, and in-hospital mortality rate. RESULTS We identified 180 patients with HF (17.4%), mean age 74.6 +/- 14; 87 were male (48%), aged 73.7 +/- 14.2, and 93 female (52%), aged 75.6 +/- 14. Left ventricular systolic dysfunction (LVSD) was present in 42.2% of cases, preserved left ventricular systolic function in 32.6%, and valvular heart disease in 10.6%. Hypertension and coronary artery disease were the main etiological risk factors (62.2% and 42.8% respectively). Atrial fibrillation was recorded in 43.4% of the patients, diabetes was diagnosed in 21.6%, and anemia and chronic obstructive pulmonary disease in about one third. Infection, predominantly respiratory, was the main factor triggering decompensation, followed by uncontrolled hypertension and supraventricular tachyarrhythmia. At admission, 42.2% of the patients were in NYHA class III and 44.8% in NYHA class IV. HF patients had a mean hospital stay of 13.8 days, slightly shorter than the mean overall stay of patients admitted to the Medical Department in the same period (14.5 days). In-hospital mortality for HF patients was 7.7%, with HF being the first cause of admission to the Medical Department, followed by stroke (10.6%). CONCLUSIONS This study confirms the high prevalence of acute or chronic decompensated HF in patients hospitalized in the Medical Department of a central teaching hospital in an urban area. The patients were mainly elderly, of both genders, with a slightly higher proportion of HF due to LVSD. Most patients were in NYHA classes III and IV. Mean hospital stay was no longer than that of all patients admitted in the same period. The in-hospital mortality rate was low. The age-group affected and the high prevalence of multiple comorbidities emphasize the need to establish HF clinics with multidisciplinary teams to manage these patients, and health authorities must be made aware of the burden of this syndrome.

UI MeSH Term Description Entries
D008297 Male Males
D011787 Quality of Health Care The levels of excellence which characterize the health service or health care provided based on accepted standards of quality. Pharmacy Audit,Quality of Care,Quality of Healthcare,Audit, Pharmacy,Care Quality,Health Care Quality,Healthcare Quality,Pharmacy Audits
D005260 Female Females
D006333 Heart Failure A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION. Cardiac Failure,Heart Decompensation,Congestive Heart Failure,Heart Failure, Congestive,Heart Failure, Left-Sided,Heart Failure, Right-Sided,Left-Sided Heart Failure,Myocardial Failure,Right-Sided Heart Failure,Decompensation, Heart,Heart Failure, Left Sided,Heart Failure, Right Sided,Left Sided Heart Failure,Right Sided Heart Failure
D006760 Hospitalization The confinement of a patient in a hospital. Hospitalizations
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000208 Acute Disease Disease having a short and relatively severe course. Acute Diseases,Disease, Acute,Diseases, Acute
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D000369 Aged, 80 and over Persons 80 years of age and older. Oldest Old
D012189 Retrospective Studies Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons. Retrospective Study,Studies, Retrospective,Study, Retrospective

Related Publications

Pedro Moraes Sarmento, and Cândida Fonseca, and Filipa Marques, and Fátima Ceia, and Ana Aleixo
January 2003, Reviews in cardiovascular medicine,
Pedro Moraes Sarmento, and Cândida Fonseca, and Filipa Marques, and Fátima Ceia, and Ana Aleixo
January 2002, Reviews in cardiovascular medicine,
Pedro Moraes Sarmento, and Cândida Fonseca, and Filipa Marques, and Fátima Ceia, and Ana Aleixo
October 2023, Journal of clinical medicine,
Pedro Moraes Sarmento, and Cândida Fonseca, and Filipa Marques, and Fátima Ceia, and Ana Aleixo
June 2018, Acta clinica Belgica,
Pedro Moraes Sarmento, and Cândida Fonseca, and Filipa Marques, and Fátima Ceia, and Ana Aleixo
October 2007, Archives of internal medicine,
Pedro Moraes Sarmento, and Cândida Fonseca, and Filipa Marques, and Fátima Ceia, and Ana Aleixo
July 2022, Angiology,
Pedro Moraes Sarmento, and Cândida Fonseca, and Filipa Marques, and Fátima Ceia, and Ana Aleixo
March 2023, Cureus,
Pedro Moraes Sarmento, and Cândida Fonseca, and Filipa Marques, and Fátima Ceia, and Ana Aleixo
December 2005, Journal of the American College of Cardiology,
Pedro Moraes Sarmento, and Cândida Fonseca, and Filipa Marques, and Fátima Ceia, and Ana Aleixo
April 2015, Deutsches Arzteblatt international,
Pedro Moraes Sarmento, and Cândida Fonseca, and Filipa Marques, and Fátima Ceia, and Ana Aleixo
January 2002, Reviews in cardiovascular medicine,
Copied contents to your clipboard!