[Changes in transient evoked otoacoustic emissions contralateral suppression in infants]. 2006

Alessandra Spada Durante, and Renata Mota Mamede Carvallo
Curso de Fonoaudiologia da Faculdade de Ciências Médicas da Santa Casa de São Paulo. asdurant@usp.br

BACKGROUND It has been suggested that the function of the medial olivocochlear system (MOCS) can be evaluated by the suppression effect of the transient evoked otoacoustic emission (TEOAE). The competitive noise has an inhibitory effect on the functioning of the outer hair-cell, reducing the level of otoacoustic emissions. Despite the fact that there is no postnatal growth of the cochlea, middle ear growth and auditory processing development continue after birth. OBJECTIVE To analyze age-related changes of MOCS using the TEOAE suppression in healthy infants. METHODS 25 full-term infants with no risk factors for hearing loss were evaluated in two moments: at birth and at the age of six months. At both ages TEOAE were recorded in the "Quickscreen" mode, nonlinear stimulation at 78dB peSPL, for both ears, with and without contralateral noise presented at 60dB SPL. RESULTS The data analyses, using ANOVA, revealed significant contralateral suppression of otoacoustic emissions in both groups, but the TEOAE levels and the amount of TEOAE contralateral suppression were smaller at six-month of age when compared to the neonatal period (p < 0.01). The TEOAE suppression effect for neonatals was 2.81dB (+/- 0.19dB) and at the age of six months was 1.41dB (+/- 0.29dB). CONCLUSIONS The amount of TEOAE suppression decreased from birth to six months of age. The association between contralateral acoustic stimulation and a commercially available rapid TEOAE measurement system enables a non-invasive monitoring of the auditory efferent mechanism and seems to be clinically feasible to evaluate cochlear status and auditory efferent function development in infants at risk.

UI MeSH Term Description Entries
D007223 Infant A child between 1 and 23 months of age. Infants
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D008297 Male Males
D009847 Olivary Nucleus A brainstem nuclear complex. in the hindbrain, also referred to as the olivary body. The olivary nuclear complex is a part of the MEDULLA OBLONGATA and the PONTINE TEGMENTUM. It is involved with motor control and is a major source of sensory input to the CEREBELLUM. Basal Nucleus, Olivary,Nucleus Basalis, Olivary,Olivary Body,Olivary Complex,Olivary Nuclei,Complex, Olivary,Nucleus, Olivary,Nucleus, Olivary Basal,Olivary Basal Nucleus,Olivary Bodies
D003051 Cochlea The part of the inner ear (LABYRINTH) that is concerned with hearing. It forms the anterior part of the labyrinth, as a snail-like structure that is situated almost horizontally anterior to the VESTIBULAR LABYRINTH. Cochleas
D005260 Female Females
D006317 Hearing Loss, Noise-Induced Hearing loss due to exposure to explosive loud noise or chronic exposure to sound level greater than 85 dB. The hearing loss is often in the frequency range 4000-6000 hertz. Acoustic Trauma,Hearing Loss, Noise Induced,Noise-Induced Hearing Loss
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000161 Acoustic Stimulation Use of sound to elicit a response in the nervous system. Auditory Stimulation,Stimulation, Acoustic,Stimulation, Auditory
D000704 Analysis of Variance A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable. ANOVA,Analysis, Variance,Variance Analysis,Analyses, Variance,Variance Analyses

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