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1. We previously reported an endogenous activator of procollagenase from the culture medium of rabbit uterine cervical fibroblasts (Ishibashi et al. (1987) Biochem. J. 241, 527-534). 2. Similar activator was also purified and characterized from rabbit synovial fibroblasts (Vater et al. (1983) J. biol. Chem. 258, 9374-9382), but its mode of activation of procollagenase was reported to be different from that of purified activator from uterine cervical fibroblasts. 3. Here we report the comparative studies of the two activators of procollagenase and demonstrate that they are identified as matrix metalloproteinase 3 (stromelysin) by their immunological and functional criteria. The specific role of the activator in procollagenase activation is also described.
A Ito, and
Y Itoh, and
T Sato, and
Y Mori, and
K Suzuki, and
H Nagase
July 1988,
Collagen and related research,
A Ito, and
Y Itoh, and
T Sato, and
Y Mori, and
K Suzuki, and
H Nagase
November 1990,
Biochemistry,
A Ito, and
Y Itoh, and
T Sato, and
Y Mori, and
K Suzuki, and
H Nagase
January 1987,
The Biochemical journal,
A Ito, and
Y Itoh, and
T Sato, and
Y Mori, and
K Suzuki, and
H Nagase
December 1990,
The Journal of biological chemistry,
A Ito, and
Y Itoh, and
T Sato, and
Y Mori, and
K Suzuki, and
H Nagase
November 1988,
Archives of biochemistry and biophysics,
A Ito, and
Y Itoh, and
T Sato, and
Y Mori, and
K Suzuki, and
H Nagase
February 2004,
Bulletin du cancer,
A Ito, and
Y Itoh, and
T Sato, and
Y Mori, and
K Suzuki, and
H Nagase
August 2004,
International journal of molecular medicine,
A Ito, and
Y Itoh, and
T Sato, and
Y Mori, and
K Suzuki, and
H Nagase
January 2005,
Histology and histopathology,
A Ito, and
Y Itoh, and
T Sato, and
Y Mori, and
K Suzuki, and
H Nagase
February 1992,
The Journal of biological chemistry,
A Ito, and
Y Itoh, and
T Sato, and
Y Mori, and
K Suzuki, and
H Nagase
February 1989,
The Biochemical journal,
