Biomaterial Database

Plaque excision in the treatment of peripheral arterial disease. 2006

Brian G Rubin

Section of Vascular Sugery, Division of Vascular Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO 63110-1094, USA. rubinb@wustl.edu

The goals of any percutaneous intervention in the lower extremity are to provide initial technical success and restore durable arterial patency. The first goal can be achieved through a multitude of endovascular techniques, whereas achieving the latter has remained elusive. The large number of choices in treatment options for percutaneous lower-extremity revascularization speak to the fact that no single tool or technique has been proven to be superior. The SilverHawk plaque excision system is designed to debulk stenotic or occlusive arterial lesions. Like many endovascular technologies, reports have focused on rates of initial technical success and short-term outcomes, but long-term results remain unknown. This report reviews selected published or presented results of plaque excision, touches on areas of concern or controversy regarding both the device and some of its proponents, and suggests clinical or anatomic settings in which plaque excision appears most effective. The ultimate utility of this technology will depend on confirmation of its acute and long-term outcomes through unbiased, well-designed clinical trials.

UI	MeSH Term	Description	Entries
D011150	Popliteal Artery	The continuation of the femoral artery coursing through the popliteal fossa; it divides into the anterior and posterior tibial arteries.	Arteria Poplitea,Artery, Popliteal,Popliteal Arteries
D004867	Equipment Design	Methods and patterns of fabricating machines and related hardware.	Design, Equipment,Device Design,Medical Device Design,Design, Medical Device,Designs, Medical Device,Device Design, Medical,Device Designs, Medical,Medical Device Designs,Design, Device,Designs, Device,Designs, Equipment,Device Designs,Equipment Designs
D005263	Femoral Artery	The main artery of the thigh, a continuation of the external iliac artery.	Common Femoral Artery,Arteries, Common Femoral,Arteries, Femoral,Artery, Common Femoral,Artery, Femoral,Common Femoral Arteries,Femoral Arteries,Femoral Arteries, Common,Femoral Artery, Common
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001157	Arterial Occlusive Diseases	Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.	Arterial Obstructive Diseases,Arterial Occlusion,Arterial Obstructive Disease,Arterial Occlusions,Arterial Occlusive Disease,Disease, Arterial Obstructive,Disease, Arterial Occlusive,Obstructive Disease, Arterial,Occlusion, Arterial,Occlusive Disease, Arterial
D017073	Atherectomy	Endovascular procedure in which atheromatous plaque is excised by a cutting or rotating catheter. It differs from balloon and laser angioplasty procedures which enlarge vessels by dilation but frequently do not remove much plaque. If the plaque is removed by surgical excision under general anesthesia rather than by an endovascular procedure through a catheter, it is called ENDARTERECTOMY.	Percutaneous Atherectomy,Percutaneous Transluminal Atherectomy,Transluminal Atherectomy,Atherectomies,Atherectomies, Percutaneous,Atherectomies, Percutaneous Transluminal,Atherectomies, Transluminal,Atherectomy, Percutaneous,Atherectomy, Percutaneous Transluminal,Atherectomy, Transluminal,Percutaneous Atherectomies,Percutaneous Transluminal Atherectomies,Transluminal Atherectomies,Transluminal Atherectomies, Percutaneous,Transluminal Atherectomy, Percutaneous