[The microsurgical treatment of the supratentorial arteriovenous malformations. Part II--complications]. 2006

Przemysław Kunert, and Andrzej Marchel
Katedra i Klinika Neurochirurgii Akademii Medycznej w Warszawie, ul.Banacha 1a, 02-097 Warszawa. pkunert@wp.pl

OBJECTIVE The aim of this study was an analysis of complications after surgical treatment of the cerebral supratentorial arteriovenous malformations (AVM), assessment of their clinical sequelae, and attempt to find factors influencing their occurrence. METHODS 88 consecutive patients operated on for AVM in the years 1983-2000 were included in a retrospective study. In all patients microsurgical, selective removal of AVM was performed, without prior embolization. The statistical analysis was carried out by means of exact Fisher test and c2 test. RESULTS Complications in the postoperative period were observed in 45.5%, including short-term deterioration (27.3%) and symptoms present till the day of discharge (18.2%). Mechanisms of deterioration were as follows: significant intraoperative hemorrhage (5.7%), hemodynamic disturbances after AVM removal (20.5%) and resection of AVM in the eloquent area (19.3%). Many variables that may contribute to the complications were studied. Factors increasing the risk of significant intraoperative hemorrhage are: steal effect visible in angiography (32% vs. 10%, p<0.05), intraventricular penetration of AVM (38% vs. 11%, p<0.05). Factors increasing the risk of hemodynamic disturbances are: feeding from the medial cerebral artery (MCA) (31% vs. 8%, p=0.02) and complex venous drainage (32% vs. 14%, p=0.05). CONCLUSIONS The most common causes of postoperative deterioration are hemodynamic disturbances after AVM removal and manipulation in the eloquent area. Hemodynamic disturbances worsened the prognosis significantly, and were the only cause of mortality (3.4%). However, massive intraoperative hemorrhage and operation in the eloquent area did not influence the outcome significantly. Risk factors for intraoperative hemorrhage are steal effect and intraventricular penetration of AVM. Risk factors for hemodynamic disturbances are feeding AVM from MCA and complex venous drainage.

UI MeSH Term Description Entries
D008297 Male Males
D008866 Microsurgery The performance of surgical procedures with the aid of a microscope.
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011183 Postoperative Complications Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery. Complication, Postoperative,Complications, Postoperative,Postoperative Complication
D002538 Intracranial Arteriovenous Malformations Congenital vascular anomalies in the brain characterized by direct communication between an artery and a vein without passing through the CAPILLARIES. The locations and size of the shunts determine the symptoms including HEADACHES; SEIZURES; STROKE; INTRACRANIAL HEMORRHAGES; mass effect; and vascular steal effect. Arteriovenous Malformations, Cerebral,Intracranial Arteriovenous Malformations, Congenital,AVM (Arteriovenous Malformation) Intracranial,Cerebral Arteriovenous Malformations,Congenital Intracranial Arteriovenous Malformations,Intracranial Arteriovenous Malformation, Ruptured,Ruptured Intracranial Arteriovenous Malformation,Arteriovenous Malformation, Cerebral,Arteriovenous Malformation, Intracranial,Arteriovenous Malformations, Intracranial,Cerebral Arteriovenous Malformation,Intracranial Arteriovenous Malformation,Malformation, Cerebral Arteriovenous,Malformation, Intracranial Arteriovenous,Malformations, Cerebral Arteriovenous,Malformations, Intracranial Arteriovenous
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D004388 Dura Mater The outermost of the three MENINGES, a fibrous membrane of connective tissue that covers the brain and the spinal cord. Falx Cerebelli,Falx Cerebri,Pachymeninx,Tentorium Cerebelli
D004621 Embolization, Therapeutic A method of hemostasis utilizing various agents such as Gelfoam, silastic, metal, glass, or plastic pellets, autologous clot, fat, and muscle as emboli. It has been used in the treatment of spinal cord and INTRACRANIAL ARTERIOVENOUS MALFORMATIONS, renal arteriovenous fistulas, gastrointestinal bleeding, epistaxis, hypersplenism, certain highly vascular tumors, traumatic rupture of blood vessels, and control of operative hemorrhage. Embolotherapy,Therapeutic Embolization,Embolizations, Therapeutic,Embolotherapies,Therapeutic Embolizations
D005260 Female Females
D005500 Follow-Up Studies Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease. Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup

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