Complications of central venous catheters in patients on home parenteral nutrition: an analysis of 68 patients over 16 years. 2006

Noriyasu Shirotani, and Takayuki Iino, and Kumiko Numata, and Shingo Kameoka
Department of Surgery II, Tokyo Women's Medical University School of Medicine, Tokyo 162-8666, Japan.

OBJECTIVE To determine the incidence of central venous catheter (CVC) complications and to analyze the potential risk factors for complications necessitating CVC removal in patients on home parenteral nutrition (HPN). METHODS We studied 68 patients on HPN (44 men and 24 women), examining the incidence of CVC complications and CVC-related infections. The risk factors for CVC-related infection were investigated using multivariate logistic regression analysis. RESULTS The incidences of CVC complications were 0.29 episodes per CVC-year in 45 patients with an external tunneled CVC, and 0.66 episodes per CVC-year in 23 patients with an implanted port device. The incidences of CVC-related infections were 0.17 episodes per CVC-year for external tunneled CVCs and 0.17 episodes per CVC-year for implanted port devices. There were no significant differences in the incidences of CVC complications (P = 0.095), and CVC-related infections (P = 0.406). The incidences of CVC-related infections were 0.04 episodes per CVC-year in 54 patients with malignancies, and 0.68 episodes in 14 patients with benign diseases (P < 0.001). Multivariate logistic regression analysis revealed the types of diseases that influenced the incidence of CVC-related infections (P < 0.05). CONCLUSIONS The incidence of CVC complications did not differ between the two groups. The type of disease was the most important predictive factor of CVC-related infections.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D002405 Catheterization, Central Venous Placement of an intravenous CATHETER in the subclavian, jugular, or other central vein. Central Venous Catheterization,Venous Catheterization, Central,Catheterization, Central,Central Catheterization,Catheterizations, Central,Catheterizations, Central Venous,Central Catheterizations,Central Venous Catheterizations,Venous Catheterizations, Central
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012307 Risk Factors An aspect of personal behavior or lifestyle, environmental exposure, inborn or inherited characteristic, which, based on epidemiological evidence, is known to be associated with a health-related condition considered important to prevent. Health Correlates,Risk Factor Scores,Risk Scores,Social Risk Factors,Population at Risk,Populations at Risk,Correlates, Health,Factor, Risk,Factor, Social Risk,Factors, Social Risk,Risk Factor,Risk Factor Score,Risk Factor, Social,Risk Factors, Social,Risk Score,Score, Risk,Score, Risk Factor,Social Risk Factor
D015994 Incidence The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases in the population at a given time. Attack Rate,Cumulative Incidence,Incidence Proportion,Incidence Rate,Person-time Rate,Secondary Attack Rate,Attack Rate, Secondary,Attack Rates,Cumulative Incidences,Incidence Proportions,Incidence Rates,Incidence, Cumulative,Incidences,Person time Rate,Person-time Rates,Proportion, Incidence,Rate, Attack,Rate, Incidence,Rate, Person-time,Rate, Secondary Attack,Secondary Attack Rates
D016009 Chi-Square Distribution A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another. Chi-Square Test,Chi Square Distribution,Chi Square Test,Chi-Square Distributions,Chi-Square Tests,Distribution, Chi-Square,Distributions, Chi-Square,Test, Chi-Square,Tests, Chi-Square
D016015 Logistic Models Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor. Logistic Regression,Logit Models,Models, Logistic,Logistic Model,Logistic Regressions,Logit Model,Model, Logistic,Model, Logit,Models, Logit,Regression, Logistic,Regressions, Logistic
D016331 Parenteral Nutrition, Home The at-home administering of nutrients for assimilation and utilization by a patient who cannot maintain adequate nutrition by enteral feeding alone. Nutrients are administered via a route other than the alimentary canal (e.g., intravenously, subcutaneously). Home Parenteral Nutrition,Nutrition, Home Parenteral,Parenteral Feeding, Home,Home Parenteral Feeding,Feeding, Home Parenteral

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