Biomaterial Database

Extrinsic allergic alveolitis. 2006

Tengku Ismail, and Charles McSharry, and Gavin Boyd

Faculty of Medicine, Universiti Teknologi MARA, Shah Alam, Malaysia, and North Glasgow University Hospitals NHS Trust, UK. tengkusaifudin@yahoo.co.uk

Extrinsic allergic alveolitis (also known as hypersensitivity pneumonitis) is caused by repeated inhalation of mainly organic antigens by sensitized subjects. This induces a hypersensitivity response in the distal bronchioles and alveoli and subjects may present clinically with a variety of symptoms. The aims of this review are to describe the current concepts of the immunological response, the diverse clinical presentation of this disease, the relevant investigations and management, and areas for future studies.

UI	MeSH Term	Description	Entries
D011379	Prognosis	A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.	Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D003937	Diagnosis, Differential	Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures.	Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D005938	Glucocorticoids	A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.	Glucocorticoid,Glucocorticoid Effect,Glucorticoid Effects,Effect, Glucocorticoid,Effects, Glucorticoid
D006680	HLA Antigens	Antigens determined by leukocyte loci found on chromosome 6, the major histocompatibility loci in humans. They are polypeptides or glycoproteins found on most nucleated cells and platelets, determine tissue types for transplantation, and are associated with certain diseases.	Human Leukocyte Antigen,Human Leukocyte Antigens,Leukocyte Antigens,HL-A Antigens,Antigen, Human Leukocyte,Antigens, HL-A,Antigens, HLA,Antigens, Human Leukocyte,Antigens, Leukocyte,HL A Antigens,Leukocyte Antigen, Human,Leukocyte Antigens, Human
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000542	Alveolitis, Extrinsic Allergic	A common interstitial lung disease caused by hypersensitivity reactions of PULMONARY ALVEOLI after inhalation of and sensitization to environmental antigens of microbial, animal, or chemical sources. The disease is characterized by lymphocytic alveolitis and granulomatous pneumonitis.	Allergic Alveolitis, Extrinsic,Hypersensitivity Pneumonitis,Pneumonitis, Hypersensitivity,Allergic Alveolitides, Extrinsic,Alveolitides, Extrinsic Allergic,Extrinsic Allergic Alveolitides,Extrinsic Allergic Alveolitis,Hypersensitivity Pneumonitides,Pneumonitides, Hypersensitivity
D001706	Biopsy	Removal and pathologic examination of specimens from the living body.	Biopsies
D016040	Lung Transplantation	The transference of either one or both of the lungs from one human or animal to another.	Grafting, Lung,Transplantation, Lung,Graftings, Lung,Lung Grafting,Lung Graftings,Lung Transplantations,Transplantations, Lung
D018893	Bronchoalveolar Lavage	Washing out of the lungs with saline or mucolytic agents for diagnostic or therapeutic purposes. It is very useful in the diagnosis of diffuse pulmonary infiltrates in immunosuppressed patients.	Bronchial Lavage,Lung Lavage,Bronchioalveolar Lavage,Bronchopulmonary Lavage,Lavage, Bronchopulmonary,Bronchial Lavages,Bronchioalveolar Lavages,Bronchoalveolar Lavages,Bronchopulmonary Lavages,Lavage, Bronchial,Lavage, Bronchioalveolar,Lavage, Bronchoalveolar,Lavage, Lung,Lavages, Bronchial,Lavages, Bronchioalveolar,Lavages, Bronchoalveolar,Lavages, Bronchopulmonary,Lavages, Lung,Lung Lavages