Biomaterial Database

Epidermolysis bullosa acquisita occurring in 2 patients with hepatitis C. 2006

Brent A Shook, and Michael J Wells, and Ronald P Rapini, and Everardo Cobos

Department of Dermatology, Texas Tech University School of Medicine, Lubbock, Texas 79430, USA.

We report 2 patients with documented chronic hepatitis C infection and epidermolysis bullosa acquisita (EBA). Both patients clinically represent classic EBA, exhibiting skin fragility and blistering occurring both spontaneously and secondary to trauma, which heal with milia and scar formation. EBA often is a disease of altered immune status and debility. Further work is necessary to show whether hepatitis C plays a causative role in EBA in these 2 patients and in general.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D016107	Epidermolysis Bullosa Acquisita	Form of epidermolysis bullosa characterized by trauma-induced, subepidermal blistering with no family history of the disease. Direct immunofluorescence shows IMMUNOGLOBULIN G deposited at the dermo-epidermal junction.	Epidermolysis Bullosa, Acquired,Acquired Form of Epidermolysis Bullosa,Acquired Epidermolysis Bullosa
D019698	Hepatitis C, Chronic	INFLAMMATION of the LIVER in humans that is caused by HEPATITIS C VIRUS lasting six months or more. Chronic hepatitis C can lead to LIVER CIRRHOSIS.	Chronic Hepatitis C