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Serum samples from 243 cases of primary hepatocellular carcinoma (PHC) and 302 non-PHC hospital controls were tested for hepatitis B virus (HBV) surface antigen (HBsAg), antibody to HBsAg (anti-HBs), antibody to HBV core antigen (anti-HBc), HBV e antigen (HBeAg) and antibody to HBeAg (anti-HBe) with radioimmunoassays using commercial kits. A total of 236 (97%) PHC cases and 302 (100%) hospital controls were positive for one or more HBV markers. While 188 (77%) PHC cases and 57 (19%) controls were positive for HBsAg, 44 (18%) PHC cases and 5 (2%) controls were positive for both BHsAg and HBeAg. Statistically significant associations with PHC were observed for HBsAg and HBeAg with an odds ratio (OR) of 10.0 and 3.2, respectively, when age, sex and other markers were adjusted. The stratification analysis of interactive effects of HBV infection markers on the development of PHC showed that HBeAg carrier status may increase PHC risk associated with HBsAg status.
T M Lin, and
C J Chen, and
S N Lu, and
A S Chang, and
Y C Chang, and
S T Hsu, and
J Y Liu, and
Y F Liaw, and
W Y Chang
January 2003,
Journal of insurance medicine (New York, N.Y.),
T M Lin, and
C J Chen, and
S N Lu, and
A S Chang, and
Y C Chang, and
S T Hsu, and
J Y Liu, and
Y F Liaw, and
W Y Chang
January 1981,
Progress in medical virology. Fortschritte der medizinischen Virusforschung. Progres en virologie medicale,
T M Lin, and
C J Chen, and
S N Lu, and
A S Chang, and
Y C Chang, and
S T Hsu, and
J Y Liu, and
Y F Liaw, and
W Y Chang
June 1982,
Current problems in cancer,
T M Lin, and
C J Chen, and
S N Lu, and
A S Chang, and
Y C Chang, and
S T Hsu, and
J Y Liu, and
Y F Liaw, and
W Y Chang
April 1983,
Gastroenterology,
T M Lin, and
C J Chen, and
S N Lu, and
A S Chang, and
Y C Chang, and
S T Hsu, and
J Y Liu, and
Y F Liaw, and
W Y Chang
January 1982,
Transactions of the Royal Society of Tropical Medicine and Hygiene,
T M Lin, and
C J Chen, and
S N Lu, and
A S Chang, and
Y C Chang, and
S T Hsu, and
J Y Liu, and
Y F Liaw, and
W Y Chang
January 1988,
Cancer investigation,
T M Lin, and
C J Chen, and
S N Lu, and
A S Chang, and
Y C Chang, and
S T Hsu, and
J Y Liu, and
Y F Liaw, and
W Y Chang
January 2004,
Annals of medicine,
T M Lin, and
C J Chen, and
S N Lu, and
A S Chang, and
Y C Chang, and
S T Hsu, and
J Y Liu, and
Y F Liaw, and
W Y Chang
December 1988,
The American journal of tropical medicine and hygiene,
T M Lin, and
C J Chen, and
S N Lu, and
A S Chang, and
Y C Chang, and
S T Hsu, and
J Y Liu, and
Y F Liaw, and
W Y Chang
January 1991,
Cancer investigation,
T M Lin, and
C J Chen, and
S N Lu, and
A S Chang, and
Y C Chang, and
S T Hsu, and
J Y Liu, and
Y F Liaw, and
W Y Chang
May 1977,
Journal of the National Cancer Institute,
