Evaluation of ionized and total serum magnesium concentrations in hyperthyroid cats. 2006

Cornelia V Gilroy, and Barbara S Horney, and Shelley A Burton, and Allan L MacKenzie
Department of Pathology and Microbiology, Atlantic Veterinary College, Charlottetown, Prince Edward Island C1A 4P3. CGilroy@upei.ca

Hyperthyroidism can increase the renal excretion of magnesium and thus cause hypomagnesemia in various species. Anaerobically collected blood samples from 15 hyperthyroid and 40 normal, healthy cats were analyzed with an ion-selective electrode analyzer and a serum biochemical analyzer. There was no significant difference in ionized or total serum magnesium concentration between the 2 groups, but there was a significant difference (P = 0.004) in the ratio of ionized to total serum magnesium concentrations between the healthy cats and the hyperthyroid cats with thyroxine (T4) concentrations at or above the median. There was a significant correlation (r = 0.894, P = 0.000) between the ionized and total magnesium concentrations in the hyperthyroid cats. The hyperthyroid cats had a significantly lower (P = 0.003) total serum protein concentration than the healthy cats. A significant negative correlation (r = -0.670, P = 0.006) was detected between the ionized magnesium and logarithmically transformed total T4 concentrations in the hyperthyroid cats, which suggests that the severity of hyperthyroidism may contribute to a decrease in the ionized magnesium concentration.

UI MeSH Term Description Entries
D006980 Hyperthyroidism Hypersecretion of THYROID HORMONES from the THYROID GLAND. Elevated levels of thyroid hormones increase BASAL METABOLIC RATE. Hyperthyroid,Primary Hyperthyroidism,Hyperthyroidism, Primary,Hyperthyroids
D008274 Magnesium A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
D008275 Magnesium Deficiency A nutritional condition produced by a deficiency of magnesium in the diet, characterized by anorexia, nausea, vomiting, lethargy, and weakness. Symptoms are paresthesias, muscle cramps, irritability, decreased attention span, and mental confusion, possibly requiring months to appear. Deficiency of body magnesium can exist even when serum values are normal. In addition, magnesium deficiency may be organ-selective, since certain tissues become deficient before others. (Harrison's Principles of Internal Medicine, 12th ed, p1936) Deficiency, Magnesium,Deficiencies, Magnesium,Magnesium Deficiencies
D008297 Male Males
D001774 Blood Chemical Analysis An examination of chemicals in the blood. Analysis, Blood Chemical,Chemical Analysis, Blood,Analyses, Blood Chemical,Blood Chemical Analyses,Chemical Analyses, Blood
D002371 Cat Diseases Diseases of the domestic cat (Felis catus or F. domesticus). This term does not include diseases of the so-called big cats such as CHEETAHS; LIONS; tigers, cougars, panthers, leopards, and other Felidae for which the heading CARNIVORA is used. Feline Diseases,Cat Disease,Disease, Cat,Disease, Feline,Diseases, Cat,Diseases, Feline,Feline Disease
D002415 Cats The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801) Felis catus,Felis domesticus,Domestic Cats,Felis domestica,Felis sylvestris catus,Cat,Cat, Domestic,Cats, Domestic,Domestic Cat
D005260 Female Females
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012720 Severity of Illness Index Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder. Illness Index Severities,Illness Index Severity

Related Publications

Cornelia V Gilroy, and Barbara S Horney, and Shelley A Burton, and Allan L MacKenzie
November 1999, Journal of the American Veterinary Medical Association,
Cornelia V Gilroy, and Barbara S Horney, and Shelley A Burton, and Allan L MacKenzie
January 2023, Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001),
Cornelia V Gilroy, and Barbara S Horney, and Shelley A Burton, and Allan L MacKenzie
January 1999, Veterinary surgery : VS,
Cornelia V Gilroy, and Barbara S Horney, and Shelley A Burton, and Allan L MacKenzie
October 1999, Research in veterinary science,
Cornelia V Gilroy, and Barbara S Horney, and Shelley A Burton, and Allan L MacKenzie
June 2003, Journal of clinical anesthesia,
Cornelia V Gilroy, and Barbara S Horney, and Shelley A Burton, and Allan L MacKenzie
January 1996, Scandinavian journal of clinical and laboratory investigation. Supplementum,
Cornelia V Gilroy, and Barbara S Horney, and Shelley A Burton, and Allan L MacKenzie
November 2005, Veterinary research communications,
Cornelia V Gilroy, and Barbara S Horney, and Shelley A Burton, and Allan L MacKenzie
January 2005, Intensive care medicine,
Cornelia V Gilroy, and Barbara S Horney, and Shelley A Burton, and Allan L MacKenzie
January 2004, Journal of anesthesia,
Cornelia V Gilroy, and Barbara S Horney, and Shelley A Burton, and Allan L MacKenzie
June 2000, Acta paediatrica (Oslo, Norway : 1992),
Copied contents to your clipboard!