Nasopharyngeal carcinoma in children: a single institution's experience. 2005

Jiunn-Ming Sheen, and Hong-Ren Yu, and Eng-Yen Huang, and Kuan-Sheng Wu, and Shiou-Huei Wei, and Chih-Cheng Hsiao
Department of Pediatrics, Chang Gung Memorial Hospital, Kaohsiung, Taiwan.

Nasopharyngeal carcinoma is a very rare disease of children. Between 1992 and 2005, 8 male and 2 female patients [ages ranging from 12 to 17 years,] were treated in our institution. The histopathologies were all undifferentiated type (WHO Type III). Of the ten patients, one was T2, five were T3, and four were T4, respectively (TNM system of the American Joint Committee for Cancer Staging). Eight patients had node metastases, 6/8 had bilateral and 4/8 had nodes larger than 6 cm. The main symptoms at diagnosis were neck mass followed by nasal, aural symptoms, cranial nerve palsy and headache. Four patients received radiotherapy only, while six patients received cisplatin-based concomitant chemoradiotherapy. The mean irradiation doses to the primary sites were 7200 cGy. Two patients developed early systemic relapse and died one year and 4 months, respectively, after relapse. After a median follow-up of 30 months, the event-free survival and overall survival were 70% and 75%, respectively. Although the sample size was small, it seemed that the patients had a good chance of survival in spite of advanced stage. However, late morbidity was a concern.

UI MeSH Term Description Entries
D008297 Male Males
D009303 Nasopharyngeal Neoplasms Tumors or cancer of the NASOPHARYNX. Cancer of Nasopharynx,Nasopharyngeal Cancer,Cancer of the Nasopharynx,Nasopharynx Cancer,Nasopharynx Neoplasms,Neoplasms, Nasopharyngeal,Cancer, Nasopharyngeal,Cancer, Nasopharynx,Cancers, Nasopharyngeal,Cancers, Nasopharynx,Nasopharyngeal Cancers,Nasopharyngeal Neoplasm,Nasopharynx Cancers,Nasopharynx Neoplasm,Neoplasm, Nasopharyngeal,Neoplasm, Nasopharynx,Neoplasms, Nasopharynx
D009367 Neoplasm Staging Methods which attempt to express in replicable terms the extent of the neoplasm in the patient. Cancer Staging,Staging, Neoplasm,Tumor Staging,TNM Classification,TNM Staging,TNM Staging System,Classification, TNM,Classifications, TNM,Staging System, TNM,Staging Systems, TNM,Staging, Cancer,Staging, TNM,Staging, Tumor,System, TNM Staging,Systems, TNM Staging,TNM Classifications,TNM Staging Systems
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths

Related Publications

Jiunn-Ming Sheen, and Hong-Ren Yu, and Eng-Yen Huang, and Kuan-Sheng Wu, and Shiou-Huei Wei, and Chih-Cheng Hsiao
January 1994, Medical and pediatric oncology,
Jiunn-Ming Sheen, and Hong-Ren Yu, and Eng-Yen Huang, and Kuan-Sheng Wu, and Shiou-Huei Wei, and Chih-Cheng Hsiao
January 2011, Journal of oncology,
Jiunn-Ming Sheen, and Hong-Ren Yu, and Eng-Yen Huang, and Kuan-Sheng Wu, and Shiou-Huei Wei, and Chih-Cheng Hsiao
January 2004, Pediatric hematology and oncology,
Jiunn-Ming Sheen, and Hong-Ren Yu, and Eng-Yen Huang, and Kuan-Sheng Wu, and Shiou-Huei Wei, and Chih-Cheng Hsiao
July 2023, Turkish archives of pediatrics,
Jiunn-Ming Sheen, and Hong-Ren Yu, and Eng-Yen Huang, and Kuan-Sheng Wu, and Shiou-Huei Wei, and Chih-Cheng Hsiao
January 2012, Journal of pediatric endocrinology & metabolism : JPEM,
Jiunn-Ming Sheen, and Hong-Ren Yu, and Eng-Yen Huang, and Kuan-Sheng Wu, and Shiou-Huei Wei, and Chih-Cheng Hsiao
January 2002, Brachytherapy,
Jiunn-Ming Sheen, and Hong-Ren Yu, and Eng-Yen Huang, and Kuan-Sheng Wu, and Shiou-Huei Wei, and Chih-Cheng Hsiao
July 2019, European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery,
Jiunn-Ming Sheen, and Hong-Ren Yu, and Eng-Yen Huang, and Kuan-Sheng Wu, and Shiou-Huei Wei, and Chih-Cheng Hsiao
November 2009, Journal of pediatric hematology/oncology,
Jiunn-Ming Sheen, and Hong-Ren Yu, and Eng-Yen Huang, and Kuan-Sheng Wu, and Shiou-Huei Wei, and Chih-Cheng Hsiao
July 2022, Medicine,
Jiunn-Ming Sheen, and Hong-Ren Yu, and Eng-Yen Huang, and Kuan-Sheng Wu, and Shiou-Huei Wei, and Chih-Cheng Hsiao
November 2014, Southern medical journal,
Copied contents to your clipboard!