Novel regulation of pyruvate dehydrogenase phosphatase activity from mitochondria of the parasitic nematode, Ascaris suum.
1991
H Song, and
J Thissen, and
R Komuniecki
Department of Biology, University of Toledo, OH 43606-3390.
UI
MeSH Term
Description
Entries
D007700
Kinetics
The rate dynamics in chemical or physical systems.
D008293
Malates
Derivatives of malic acid (the structural formula: (COO-)2CH2CHOH), including its salts and esters.
D008928
Mitochondria
Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Each mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. They contain distinctive RIBOSOMES, transfer RNAs (RNA, TRANSFER); AMINO ACYL T RNA SYNTHETASES; and elongation and termination factors. Mitochondria depend upon genes within the nucleus of the cells in which they reside for many essential messenger RNAs (RNA, MESSENGER). Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes. (King & Stansfield, A Dictionary of Genetics, 4th ed)
(Pyruvate dehydrogenase (lipoamide))-phosphate phosphohydrolase. A mitochondrial enzyme that catalyzes the hydrolytic removal of a phosphate on a specific seryl hydroxyl group of pyruvate dehydrogenase, reactivating the enzyme complex. EC 3.1.3.43.
Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.
Animal,Metazoa,Animalia
D001200
Ascaris
A genus of nematodes of the superfamily ASCARIDOIDEA whose species usually inhabit the intestine.