Biomaterial Database

Shaped regeneration of rabbit ear perichondrium. 1991

M M Ruuskanen

Department of Surgery, Oulu University Central Hospital, Finland.

The neocartilage that regenerated from the ear perichondrium in 18 growing rabbits was shaped using biodegradable implants. The animals were divided into two groups according to the operation used. In group 1 a self-reinforced polyglycolic acid (SR-PGA) rod was placed inside a perichondrial pocket on the dorsum of the ear and surrounded by blood clot, and in group 2 a flap of ear perichondrium was shaped around an SR-PGA rod. Samples were taken for histological examination six weeks after the operation. Active growth of neocartilage was seen in both groups and the SR-PGA rod had successfully guided the perichondrial regeneration in most of the animals.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D011100	Polyglycolic Acid	A biocompatible polymer used as a surgical suture material.	Polyglycolide,Biofix,Dexon (Polyester),Dexon-S,Dexon S,DexonS
D011817	Rabbits	A burrowing plant-eating mammal with hind limbs that are longer than its fore limbs. It belongs to the family Leporidae of the order Lagomorpha, and in contrast to hares, possesses 22 instead of 24 pairs of chromosomes.	Belgian Hare,New Zealand Rabbit,New Zealand Rabbits,New Zealand White Rabbit,Rabbit,Rabbit, Domestic,Chinchilla Rabbits,NZW Rabbits,New Zealand White Rabbits,Oryctolagus cuniculus,Chinchilla Rabbit,Domestic Rabbit,Domestic Rabbits,Hare, Belgian,NZW Rabbit,Rabbit, Chinchilla,Rabbit, NZW,Rabbit, New Zealand,Rabbits, Chinchilla,Rabbits, Domestic,Rabbits, NZW,Rabbits, New Zealand,Zealand Rabbit, New,Zealand Rabbits, New,cuniculus, Oryctolagus
D012038	Regeneration	The physiological renewal, repair, or replacement of tissue.	Endogenous Regeneration,Regeneration, Endogenous,Regenerations
D003238	Connective Tissue	Tissue that supports and binds other tissues. It consists of CONNECTIVE TISSUE CELLS embedded in a large amount of EXTRACELLULAR MATRIX.	Connective Tissues,Tissue, Connective,Tissues, Connective
D004425	Ear Cartilage	Cartilage of the EAR AURICLE and the EXTERNAL EAR CANAL.	Auricular Cartilage,Ear Cartilages,External Ear Cartilage,Auricular Cartilages,Cartilage, Auricular,Cartilage, Ear,Cartilage, External Ear,Cartilages, Auricular,Cartilages, Ear,Cartilages, External Ear,External Ear Cartilages
D005260	Female		Females
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D019736	Prostheses and Implants	Artificial substitutes for body parts, and materials inserted into tissue for functional, cosmetic, or therapeutic purposes. Prostheses can be functional, as in the case of artificial arms and legs, or cosmetic, as in the case of an artificial eye. Implants, all surgically inserted or grafted into the body, tend to be used therapeutically. IMPLANTS, EXPERIMENTAL is available for those used experimentally.	Implants, Artificial,Prostheses and Implant,Prosthesis,Prosthetic Implant,Endoprostheses,Endoprosthesis,Prostheses,Prosthetic Implants,Artificial Implant,Artificial Implants,Implant and Prostheses,Implant, Artificial,Implant, Prosthetic,Implants and Prostheses,Implants, Prosthetic