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A rat brain cDNA probe was used to localize a gene encoding the alpha 1 subunit of neuronal dihydropyridine-sensitive L-type calcium channels in the mouse and human genomes. Hybridization of the probe to Southern blots made with DNAs from a Chinese hamster x mouse somatic cell hybrid panel indicated that this gene maps to mouse chromosome 14 (Chr 14). Southern blot analysis of an intersubspecies cross demonstrated that the calcium channel alpha 1 subunit gene, termed Cchl1a2, can be positioned 7.5 cM proximal to Np-1. Similarly, segregation among human X rodent somatic cell hybrids indicated that CCHL1A2 maps to human chromosome 3. These assignments are consistent with a region of linkage homology between human chromosome 3p and a proximal region of mouse Chr 14.
H M Chin, and
C A Kozak, and
H L Kim, and
B Mock, and
O W McBride
August 1992,
Genomics,
H M Chin, and
C A Kozak, and
H L Kim, and
B Mock, and
O W McBride
February 1998,
Mammalian genome : official journal of the International Mammalian Genome Society,
H M Chin, and
C A Kozak, and
H L Kim, and
B Mock, and
O W McBride
February 1996,
Molecular pharmacology,
H M Chin, and
C A Kozak, and
H L Kim, and
B Mock, and
O W McBride
February 2000,
Molecular and cellular probes,
H M Chin, and
C A Kozak, and
H L Kim, and
B Mock, and
O W McBride
April 1997,
Mammalian genome : official journal of the International Mammalian Genome Society,
H M Chin, and
C A Kozak, and
H L Kim, and
B Mock, and
O W McBride
June 1995,
Cellular and molecular neurobiology,
H M Chin, and
C A Kozak, and
H L Kim, and
B Mock, and
O W McBride
January 1985,
Nature,
H M Chin, and
C A Kozak, and
H L Kim, and
B Mock, and
O W McBride
January 2010,
Anesthesiology,
H M Chin, and
C A Kozak, and
H L Kim, and
B Mock, and
O W McBride
August 1994,
Mammalian genome : official journal of the International Mammalian Genome Society,
H M Chin, and
C A Kozak, and
H L Kim, and
B Mock, and
O W McBride
January 2005,
Molecular and cellular biochemistry,
