Biomaterial Database

Paraneoplastic encephalomyelitis: a case report and review of the literature. 2006

Michael Duff, and Kathryn E Dusenbery, and Fausto J Rodriguez

University of Minnesota Department of Therapeutic Radiology, MMC 494, 420 Delaware Street SE, Minneapolis, MN 55455, USA. duff0118@umn.edu

BACKGROUND The incidence of paraneoplastic syndromes varies with tumor histology. Uterine sarcomas rarely cause paraneoplastic syndromes. Furthermore, paraneoplastic encephalomyelitis has never been reported to accompany a uterine leiomyosarcoma. METHODS A 44-year-old female developed an ANNA-1 paraneoplastic encephalomyelitis after a diagnosis of a uterine leiomyosarcoma. CONCLUSIONS Paraneoplastic encephalomyelitis usually causes progressive neurologic decline. Treatment rarely alters this course.

UI	MeSH Term	Description	Entries
D007890	Leiomyosarcoma	A sarcoma containing large spindle cells of smooth muscle. Although it rarely occurs in soft tissue, it is common in the viscera. It is the most common soft tissue sarcoma of the gastrointestinal tract and uterus. The median age of patients is 60 years. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1865)	Leiomyosarcoma, Epithelioid,Leiomyosarcoma, Myxoid,Epithelioid Leiomyosarcoma,Epithelioid Leiomyosarcomas,Leiomyosarcomas,Leiomyosarcomas, Epithelioid,Leiomyosarcomas, Myxoid,Myxoid Leiomyosarcoma,Myxoid Leiomyosarcomas
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D014594	Uterine Neoplasms	Tumors or cancer of the UTERUS.	Cancer of Uterus,Uterine Cancer,Cancer of the Uterus,Neoplasms, Uterine,Neoplasms, Uterus,Uterus Cancer,Uterus Neoplasms,Cancer, Uterine,Cancer, Uterus,Cancers, Uterine,Cancers, Uterus,Neoplasm, Uterine,Neoplasm, Uterus,Uterine Cancers,Uterine Neoplasm,Uterus Cancers,Uterus Neoplasm
D017809	Fatal Outcome	Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.	Fatal Outcomes,Outcome, Fatal,Outcomes, Fatal
D020361	Paraneoplastic Syndromes, Nervous System	Degenerative or inflammatory conditions affecting the central or peripheral nervous system that develop in association with a systemic neoplasm without direct invasion by tumor. They may be associated with circulating antibodies that react with the affected neural tissue. (Intern Med 1996 Dec;35(12):925-9)	Paraneoplastic Autonomic Dysfunction,Paraneoplastic Encephalomyelitis,Autonomic Dysfunction, Paraneoplastic,Nervous System Paraneoplastic Syndromes,Paraneoplastic Neurologic Syndromes,Autonomic Dysfunctions, Paraneoplastic,Encephalomyelitis, Paraneoplastic,Neurologic Syndrome, Paraneoplastic,Neurologic Syndromes, Paraneoplastic,Paraneoplastic Autonomic Dysfunctions,Paraneoplastic Encephalomyelitides,Paraneoplastic Neurologic Syndrome,Syndrome, Paraneoplastic Neurologic,Syndromes, Paraneoplastic Neurologic