Biomaterial Database

Early foetal programming of hepatic gluconeogenesis: Glucocorticoids strike back. 2006

C E McCurdy, and J E Friedman

Department of Pediatrics, University of Colorado School of Medicine, Mail Stop 8106, Aurora, CO, 80045, USA. carrie.mccurdy@uchsc.edu

UI	MeSH Term	Description	Entries
D008099	Liver	A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.	Livers
D005938	Glucocorticoids	A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.	Glucocorticoid,Glucocorticoid Effect,Glucorticoid Effects,Effect, Glucocorticoid,Effects, Glucorticoid
D005943	Gluconeogenesis	Biosynthesis of GLUCOSE from nonhexose or non-carbohydrate precursors, such as LACTATE; PYRUVATE; ALANINE; and GLYCEROL.
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006943	Hyperglycemia	Abnormally high BLOOD GLUCOSE level.	Postprandial Hyperglycemia,Hyperglycemia, Postprandial,Hyperglycemias,Hyperglycemias, Postprandial,Postprandial Hyperglycemias
D047109	Fetal Development	Morphological and physiological development of FETUSES.	Fetal Programming,Fetal Growth,Development, Fetal,Fetal Programmings,Growth, Fetal
D051557	Hepatocyte Nuclear Factor 4	A subfamily of nuclear receptors that regulate GENETIC TRANSCRIPTION of a diverse group of GENES involved in the synthesis of BLOOD COAGULATION FACTORS; and in GLUCOSE; CHOLESTEROL; and FATTY ACIDS metabolism.	HNF4 Transcription Factor,Hepatocyte Nuclear Factor 4-alpha,Hepatocyte Nuclear Factor 4-beta,Hepatocyte Nuclear Factor 4-gamma,Hepatocyte Nuclear Factor-Forkhead Homolog 4,Nuclear Receptor Subfamily 2 Group A, Member 2,Nuclear Receptor Subfamily 2, Group A, Member 1,Hepatocyte Nuclear Factor 4 alpha,Hepatocyte Nuclear Factor 4 beta,Hepatocyte Nuclear Factor 4 gamma,Hepatocyte Nuclear Factor Forkhead Homolog 4,Transcription Factor, HNF4