| D007249 |
Inflammation |
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. |
Innate Inflammatory Response,Inflammations,Inflammatory Response, Innate,Innate Inflammatory Responses |
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| D009361 |
Neoplasm Invasiveness |
Ability of neoplasms to infiltrate and actively destroy surrounding tissue. |
Invasiveness, Neoplasm,Neoplasm Invasion,Invasion, Neoplasm |
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| D009369 |
Neoplasms |
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. |
Benign Neoplasm,Cancer,Malignant Neoplasm,Tumor,Tumors,Benign Neoplasms,Malignancy,Malignant Neoplasms,Neoplasia,Neoplasm,Neoplasms, Benign,Cancers,Malignancies,Neoplasias,Neoplasm, Benign,Neoplasm, Malignant,Neoplasms, Malignant |
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| D009389 |
Neovascularization, Pathologic |
A pathologic process consisting of the proliferation of blood vessels in abnormal tissues or in abnormal positions. |
Angiogenesis, Pathologic,Angiogenesis, Pathological,Neovascularization, Pathological,Pathologic Angiogenesis,Pathologic Neovascularization,Pathological Angiogenesis,Pathological Neovascularization |
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| D002455 |
Cell Division |
The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION. |
M Phase,Cell Division Phase,Cell Divisions,Division Phase, Cell,Division, Cell,Divisions, Cell,M Phases,Phase, Cell Division,Phase, M,Phases, M |
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| D004249 |
DNA Damage |
Injuries to DNA that introduce deviations from its normal, intact structure and which may, if left unrepaired, result in a MUTATION or a block of DNA REPLICATION. These deviations may be caused by physical or chemical agents and occur by natural or unnatural, introduced circumstances. They include the introduction of illegitimate bases during replication or by deamination or other modification of bases; the loss of a base from the DNA backbone leaving an abasic site; single-strand breaks; double strand breaks; and intrastrand (PYRIMIDINE DIMERS) or interstrand crosslinking. Damage can often be repaired (DNA REPAIR). If the damage is extensive, it can induce APOPTOSIS. |
DNA Injury,DNA Lesion,DNA Lesions,Genotoxic Stress,Stress, Genotoxic,Injury, DNA,DNA Injuries |
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| D006133 |
Growth Substances |
Signal molecules that are involved in the control of cell growth and differentiation. |
Mitogens, Endogenous,Endogenous Mitogens |
|
| D006801 |
Humans |
Members of the species Homo sapiens. |
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man |
|
| D000097782 |
NF-kappaB-Inducing Kinase |
A protein serine-threonine kinase that catalyzes the activation of canonical and non-canonical NF-kappaB pathways. |
MAP3K14 Kinase,Mitogen-Activated Protein Kinase Kinase Kinase 14,NF-kappa B Kinase,NF-kappa-B-Inducing Kinase (NIK),NFkB Kinase,NIK Protein,Nuclear Factor kappa B Kinase,B Kinase, NF-kappa,Kinase, MAP3K14,Kinase, NF-kappa B,Kinase, NF-kappaB-Inducing,Kinase, NFkB,Mitogen Activated Protein Kinase Kinase Kinase 14,NF kappa B Kinase,NF kappaB Inducing Kinase,Protein, NIK |
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| D000818 |
Animals |
Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. |
Animal,Metazoa,Animalia |
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