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Dipeptidyl aminopeptidase IV activity staining was performed in various thyroid tissues to evaluate this enzyme activity as a thyroid tumor marker. A total of 195 thyroid tissues were tested for their enzyme activity expression. All papillary and follicular carcinomas, 40 cases and 3 cases, respectively, showed enzyme activity, although two other carcinomas, one medullary and one anaplastic, were not stained. Follicular adenoma expressed enzyme activity in 4 of 26 cases. Fifty-two cases with adenomatous goiter, 54 with Graves' disease and 13 with chronic thyroiditis were judged to be negative. Five normal thyroids expressed no activity except for occasional positive staining of capillary endothelia. These data suggest that dipeptidyl aminopeptidase IV activity staining is very useful for pathological diagnosis of thyroid tumors.
T Kotani, and
Y Aratake, and
Y Ogata, and
K Umeki, and
Y Araki, and
K Hirai, and
K Kuma, and
S Ohtaki
July 1999,
Diagnostic cytopathology,
T Kotani, and
Y Aratake, and
Y Ogata, and
K Umeki, and
Y Araki, and
K Hirai, and
K Kuma, and
S Ohtaki
January 1998,
Acta cytologica,
T Kotani, and
Y Aratake, and
Y Ogata, and
K Umeki, and
Y Araki, and
K Hirai, and
K Kuma, and
S Ohtaki
July 1998,
Diagnostic cytopathology,
T Kotani, and
Y Aratake, and
Y Ogata, and
K Umeki, and
Y Araki, and
K Hirai, and
K Kuma, and
S Ohtaki
February 1996,
The Journal of otolaryngology,
T Kotani, and
Y Aratake, and
Y Ogata, and
K Umeki, and
Y Araki, and
K Hirai, and
K Kuma, and
S Ohtaki
January 1996,
Acta cytologica,
T Kotani, and
Y Aratake, and
Y Ogata, and
K Umeki, and
Y Araki, and
K Hirai, and
K Kuma, and
S Ohtaki
January 1998,
Endocrine pathology,
T Kotani, and
Y Aratake, and
Y Ogata, and
K Umeki, and
Y Araki, and
K Hirai, and
K Kuma, and
S Ohtaki
September 1996,
Annales de pathologie,
T Kotani, and
Y Aratake, and
Y Ogata, and
K Umeki, and
Y Araki, and
K Hirai, and
K Kuma, and
S Ohtaki
January 2004,
Archives of surgery (Chicago, Ill. : 1960),
T Kotani, and
Y Aratake, and
Y Ogata, and
K Umeki, and
Y Araki, and
K Hirai, and
K Kuma, and
S Ohtaki
June 1981,
Biochemical medicine,
T Kotani, and
Y Aratake, and
Y Ogata, and
K Umeki, and
Y Araki, and
K Hirai, and
K Kuma, and
S Ohtaki
March 1982,
Molecular and cellular biochemistry,
