Comparison of nasal smear eosinophilia with skin prick test positivity in patients with allergic rhinitis. 2006

Arif Sanli, and Sedat Aydin, and Günay Ateş, and Mehmet Eken, and Ozlem Celebi
Department of Otolaryngology, Dr. Lütfi Kirdar Kartal Training and Research Hospital, Istanbul, Turkey.

OBJECTIVE The aim of this study was to compare the usefulness of nasal smear eosinophilia with skin prick test for the diagnosis of allergic rhinitis and to determine the degree of correlation between the tests. METHODS Forty-one patients (16 males, 25 females; mean age 35.17; range 14 to 56 years) with a clinical history suggestive of nasal allergy and fifteen controls (7 males, 8 females; mean age 27.6; range 16 to 40 years) without any history of allergy were enrolled in this study. Skin sensitivity tests were applied in both groups. Nasal smear was examined by light microscopy. RESULTS A positive skin test reaction was demonstrated in 73.2% of the study group and in 20% of the controls, whereas 73.2% of the patients and 13.3% of the controls demonstrated significant nasal smear eosinophilia. There was 25.5% correlation between the skin prick test and nasal smear eosinophilia, although this was not statistically significant. CONCLUSIONS Both the skin prick test and nasal smear eosinophilia showed correlation with clinical history, but there was no statistically significant correlation between the two tests.

UI MeSH Term Description Entries
D007428 Intradermal Tests Skin tests in which the sensitizer is injected. Passive Transfer Test,Prausnitz-Kustner Test,Intradermal Test,Passive Transfer Tests,Prausnitz Kustner Test,Test, Intradermal,Test, Passive Transfer,Test, Prausnitz-Kustner,Tests, Intradermal,Tests, Passive Transfer
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009297 Nasal Mucosa The mucous lining of the NASAL CAVITY, including lining of the nostril (vestibule) and the OLFACTORY MUCOSA. Nasal mucosa consists of ciliated cells, GOBLET CELLS, brush cells, small granule cells, basal cells (STEM CELLS) and glands containing both mucous and serous cells. Nasal Epithelium,Schneiderian Membrane,Epithelium, Nasal,Membrane, Schneiderian,Mucosa, Nasal
D009299 Nasal Provocation Tests Application of allergens to the nasal mucosa. Interpretation includes observation of nasal symptoms, rhinoscopy, and rhinomanometry. Nasal provocation tests are used in the diagnosis of nasal hypersensitivity, including RHINITIS, ALLERGIC, SEASONAL. Provocation Tests, Nasal,Nasal Provocation Test,Provocation Test, Nasal,Test, Nasal Provocation,Tests, Nasal Provocation
D011237 Predictive Value of Tests In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test. Negative Predictive Value,Positive Predictive Value,Predictive Value Of Test,Predictive Values Of Tests,Negative Predictive Values,Positive Predictive Values,Predictive Value, Negative,Predictive Value, Positive
D004802 Eosinophilia Abnormal increase of EOSINOPHILS in the blood, tissues or organs. Eosinophilia, Tropical,Hypereosinophilia,Tropical Eosinophilia,Hypereosinophilias,Tropical Eosinophilias
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths

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