Biomaterial Database

Intrahepatic segmental primary sclerosing cholangitis: report of a case. 2006

Taku Matsumoto, and Tetsuo Ajiki, and Ippei Matsumoto, and Masahiro Tominaga, and Hiroshige Hori, and Yoshiyasu Mita, and Tsunenori Fujita, and Yasuhiro Fujino, and Yasuyuki Suzuki, and Yonson Ku, and Yoshikazu Kuroda

Department of Gastroenterological Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.

A 67-year-old woman was referred to our hospital for investigation of epigastric discomfort. Computed tomography (CT) showed dilatation of the intrahepatic bile duct in the left lobe of the liver, endoscopic cholangiography showed complete stenosis of the left main branch of intrahepatic bile duct, and CT during angiography showed decreased portal blood flow to segment 3 of the liver. Based on these findings, we suspected intrahepatic cholangiocarcinoma and performed left lobectomy of the liver. However, pathological examination revealed fibrosis and infiltration of inflammatory lymphoid cells around the stenotic bile duct and periportal area, without any evidence of malignancy. Since these findings were compatible with sclerosing cholangitis and the patient did not have a disorder that would cause secondary sclerosing cholangitis, the final diagnosis was primary sclerosing cholangitis (PSC). It is difficult to distinguish segmental PSC from cholangiocarcinoma; thus we think surgical resection is an appropriate therapeutic and diagnostic procedure for segmental intrahepatic bile duct stenosis.

UI	MeSH Term	Description	Entries
D003937	Diagnosis, Differential	Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures.	Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly
D001650	Bile Duct Neoplasms	Tumors or cancer of the BILE DUCTS.	Bile Duct Cancer,Cancer of Bile Duct,Cancer of the Bile Duct,Neoplasms, Bile Duct,Bile Duct Cancers,Bile Duct Neoplasm,Cancer, Bile Duct,Cancers, Bile Duct,Neoplasm, Bile Duct
D001653	Bile Ducts, Intrahepatic	Passages within the liver for the conveyance of bile. Includes right and left hepatic ducts even though these may join outside the liver to form the common hepatic duct.	Bile Duct, Intrahepatic,Duct, Intrahepatic Bile,Ducts, Intrahepatic Bile,Intrahepatic Bile Duct,Intrahepatic Bile Ducts
D015209	Cholangitis, Sclerosing	Chronic inflammatory disease of the BILIARY TRACT. It is characterized by fibrosis and hardening of the intrahepatic and extrahepatic biliary ductal systems leading to bile duct strictures, CHOLESTASIS, and eventual BILIARY CIRRHOSIS.	Cholangiitis, Sclerosing,Cholangitis, Primary Sclerosing,Primary Sclerosing Cholangitis,Sclerosing Cholangitis,Cholangiitides, Sclerosing,Cholangitides, Primary Sclerosing,Cholangitides, Sclerosing,Primary Sclerosing Cholangitides,Sclerosing Cholangiitides,Sclerosing Cholangiitis,Sclerosing Cholangitides,Sclerosing Cholangitides, Primary,Sclerosing Cholangitis, Primary
D018281	Cholangiocarcinoma	A malignant tumor arising from the epithelium of the BILE DUCTS.	Cholangiocellular Carcinoma,Extrahepatic Cholangiocarcinoma,Intrahepatic Cholangiocarcinoma,Carcinoma, Cholangiocellular,Carcinomas, Cholangiocellular,Cholangiocarcinoma, Extrahepatic,Cholangiocarcinoma, Intrahepatic,Cholangiocarcinomas,Cholangiocarcinomas, Extrahepatic,Cholangiocarcinomas, Intrahepatic,Cholangiocellular Carcinomas,Extrahepatic Cholangiocarcinomas,Intrahepatic Cholangiocarcinomas