Since the introduction of fluoridated toothpaste more than 30 years ago, it has become by far the most widespread source of fluoride in the world and after fluoridated water the most effective at reducing dental caries. Both the total soluble and the soluble ionic fluoride present in toothpaste are important in determining the effectiveness of the paste as it is important in remineralising demineralised lesions, a characteristic of fluoride which has proven to be the most important in preventing dental caries. The purpose of this study was to evaluate toothpaste currently available to the South African public regarding total soluble and soluble ionic fluoride. A variation of the method used by Grobler et al. (1983) and Du Preez et al. (1993) in previous studies conducted in South Africa was used in preparing the samples for fluoride analysis. Measurements of fluoride concentrations were done using an ionselective electrode. For all toothpaste studied (n=62), large variations occurred for the soluble ionic fluoride (mean = 318.44 microg F/g toothpaste; median = 139.69; standard deviation = 398.77). Correspondingly a mean total soluble fluoride of 848.84 microg F/g toothpaste was found (standard deviation = 189.35; median = 857.38). From this study it can be concluded that fluoride concentrations in toothpaste available to the South African public are in line with those found in the two previous South African studies. In the absence of artificially fluoridated water, toothpaste remains the most cost-effective strategy in the prevention of dental caries in South Africa.