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The placental changes which followed continuous infusion of cortisol into the sheep foetus in the later stages of gestation were, like the hormonal changes, broadly similar to those of spontaneous parturition. There was, however, a premature separation of foetal and maternal tissues in certain areas of the placental cotyledons, and this separation appeared to protect the foetal epithelium from the degenerative changes which normally take place in the short space of time between the birth of the lamb and the delivery of the foetal membranes. The results suggest that an experimental model in which premature labour is induced by the administration of cortisol to the foetus is probably incomplete, and that additional factors almost certainly contribute to the cascade phenomenon of spontaneous parturition.
P M Jack, and
P W Nathanielsz, and
A L Thomas, and
D H Steven
December 1976,
The Journal of physiology,
P M Jack, and
P W Nathanielsz, and
A L Thomas, and
D H Steven
July 1978,
Quarterly journal of experimental physiology and cognate medical sciences,
P M Jack, and
P W Nathanielsz, and
A L Thomas, and
D H Steven
January 1975,
Quarterly journal of experimental physiology and cognate medical sciences,
P M Jack, and
P W Nathanielsz, and
A L Thomas, and
D H Steven
October 1979,
Quarterly journal of experimental physiology and cognate medical sciences,
P M Jack, and
P W Nathanielsz, and
A L Thomas, and
D H Steven
May 1977,
Canadian Anaesthetists' Society journal,
P M Jack, and
P W Nathanielsz, and
A L Thomas, and
D H Steven
January 1973,
Endokrynologia Polska,
P M Jack, and
P W Nathanielsz, and
A L Thomas, and
D H Steven
September 1999,
Neurology India,
P M Jack, and
P W Nathanielsz, and
A L Thomas, and
D H Steven
October 1968,
The Journal of endocrinology,
P M Jack, and
P W Nathanielsz, and
A L Thomas, and
D H Steven
August 1976,
American journal of veterinary research,
P M Jack, and
P W Nathanielsz, and
A L Thomas, and
D H Steven
January 1986,
Arkhiv patologii,
