BIOMAT Database Logo BIOMAT Database Logo

Developments in and experience of kilovoltage X-ray cone beam image-guided radiotherapy. 2006

C J Moore, and A Amer, and T Marchant, and J R Sykes, and J Davies, and J Stratford, and C McCarthy, and C MacBain, and A Henry, and P Price, and P C Williams
North Western Medical Physics Department, Christie Hospital, Manchester M20 4BX, UK.

This paper offers a realistic review of kilovoltage X-ray cone beam tomography integrated with the treatment machine for image-guided radiotherapy in the light of experience taking a commercial system from prototype development into clinical use. It shows that key practicalities cannot be ignored, in particular the regular characterization of mechanical flex during gantry rotation, the mapping of defects in flat panel image transducers and their response to X-ray exposure. The number of X-ray projections and the doses required for clinically useful cone beam reconstruction at different therapy sites are considered in the context of imaging that is fit for purpose. Three roles for cone beam tomography in radiotherapy are identified: patient setup in three dimensions (3D), where even low dose cone beam tissue detail is superior to megavoltage imaging; disease targeting where, despite wide field scatter and slow scanning, it is possible to generate images that are suitable for tumour delineation even at challenging sites; adaptive treatment planning, where calibrated cone beam images have been shown to provide sufficient target detail to support "plan of the day" selection and have the potential for planning with bulk corrections. With frequent use in mind, the need to limit patient dose during setup, yet maximize much needed image quality in the target zone, is considered. Finally, it is noted that the development of cone beam tomography for radiotherapy is far from complete, with X-ray source, image transducer, reconstruction algorithms and techniques for image profile collection still being researched.

UI MeSH Term Description Entries
D011879 Radiotherapy Dosage The total amount of radiation absorbed by tissues as a result of radiotherapy. Dosage, Radiotherapy,Dosages, Radiotherapy,Radiotherapy Dosages
D011880 Radiotherapy Planning, Computer-Assisted Computer-assisted mathematical calculations of beam angles, intensities of radiation, and duration of irradiation in radiotherapy. Computer-Assisted Radiotherapy Planning,Dosimetry Calculations, Computer-Assisted,Planning, Computer-Assisted Radiotherapy,Calculation, Computer-Assisted Dosimetry,Calculations, Computer-Assisted Dosimetry,Computer Assisted Radiotherapy Planning,Computer-Assisted Dosimetry Calculation,Computer-Assisted Dosimetry Calculations,Dosimetry Calculation, Computer-Assisted,Dosimetry Calculations, Computer Assisted,Planning, Computer Assisted Radiotherapy,Radiotherapy Planning, Computer Assisted
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014057 Tomography, X-Ray Computed Tomography using x-ray transmission and a computer algorithm to reconstruct the image. CAT Scan, X-Ray,CT Scan, X-Ray,Cine-CT,Computerized Tomography, X-Ray,Electron Beam Computed Tomography,Tomodensitometry,Tomography, Transmission Computed,X-Ray Tomography, Computed,CAT Scan, X Ray,CT X Ray,Computed Tomography, X-Ray,Computed X Ray Tomography,Computerized Tomography, X Ray,Electron Beam Tomography,Tomography, X Ray Computed,Tomography, X-Ray Computer Assisted,Tomography, X-Ray Computerized,Tomography, X-Ray Computerized Axial,Tomography, Xray Computed,X Ray Computerized Tomography,X Ray Tomography, Computed,X-Ray Computer Assisted Tomography,X-Ray Computerized Axial Tomography,Beam Tomography, Electron,CAT Scans, X-Ray,CT Scan, X Ray,CT Scans, X-Ray,CT X Rays,Cine CT,Computed Tomography, Transmission,Computed Tomography, X Ray,Computed Tomography, Xray,Computed X-Ray Tomography,Scan, X-Ray CAT,Scan, X-Ray CT,Scans, X-Ray CAT,Scans, X-Ray CT,Tomographies, Computed X-Ray,Tomography, Computed X-Ray,Tomography, Electron Beam,Tomography, X Ray Computer Assisted,Tomography, X Ray Computerized,Tomography, X Ray Computerized Axial,Transmission Computed Tomography,X Ray Computer Assisted Tomography,X Ray Computerized Axial Tomography,X Ray, CT,X Rays, CT,X-Ray CAT Scan,X-Ray CAT Scans,X-Ray CT Scan,X-Ray CT Scans,X-Ray Computed Tomography,X-Ray Computerized Tomography,Xray Computed Tomography
D014965 X-Rays Penetrating electromagnetic radiation emitted when the inner orbital electrons of an atom are excited and release radiant energy. X-ray wavelengths range from 1 pm to 10 nm. Hard X-rays are the higher energy, shorter wavelength X-rays. Soft x-rays or Grenz rays are less energetic and longer in wavelength. The short wavelength end of the X-ray spectrum overlaps the GAMMA RAYS wavelength range. The distinction between gamma rays and X-rays is based on their radiation source. Grenz Ray,Grenz Rays,Roentgen Ray,Roentgen Rays,X Ray,X-Ray,Xray,Radiation, X,X-Radiation,Xrays,Ray, Grenz,Ray, Roentgen,Ray, X,Rays, Grenz,Rays, Roentgen,Rays, X,X Radiation,X Rays,X-Radiations
D015641 Radiography, Interventional Diagnostic and therapeutic procedures that are invasive or surgical in nature, and require the expertise of a specially trained radiologist. In general, they are more invasive than diagnostic imaging but less invasive than major surgery. They often involve catheterization, fluoroscopy, or computed tomography. Some examples include percutaneous transhepatic cholangiography, percutaneous transthoracic biopsy, balloon angioplasty, and arterial embolization. Interventional Radiography
D020266 Radiotherapy, Conformal A therapy using IONIZING RADIATION where there is improved dose homogeneity within the tumor and reduced dosage to uninvolved structures. The precise shaping of dose distribution is achieved via the use of computer-controlled multileaf collimators. Conformal Radiotherapy,3-D Conformal Radiotherapy,Three-Dimensional Conformal Radiotherapy,3-D Conformal Radiotherapies,Conformal Radiotherapies,Conformal Radiotherapies, 3-D,Conformal Radiotherapies, Three-Dimensional,Conformal Radiotherapy, 3-D,Conformal Radiotherapy, Three-Dimensional,Radiotherapies, 3-D Conformal,Radiotherapies, Conformal,Radiotherapies, Three-Dimensional Conformal,Radiotherapy, 3-D Conformal,Radiotherapy, Three-Dimensional Conformal,Three Dimensional Conformal Radiotherapy,Three-Dimensional Conformal Radiotherapies

Related Publications

C J Moore, and A Amer, and T Marchant, and J R Sykes, and J Davies, and J Stratford, and C McCarthy, and C MacBain, and A Henry, and P Price, and P C Williams
Image-guided radiotherapy using a mobile kilovoltage x-ray device.
January 2006, Medical dosimetry : official journal of the American Association of Medical Dosimetrists,
C J Moore, and A Amer, and T Marchant, and J R Sykes, and J Davies, and J Stratford, and C McCarthy, and C MacBain, and A Henry, and P Price, and P C Williams
Contrast medium-assisted stereotactic image-guided radiotherapy using kilovoltage cone-beam computed tomography.
November 2008, Radiation medicine,
C J Moore, and A Amer, and T Marchant, and J R Sykes, and J Davies, and J Stratford, and C McCarthy, and C MacBain, and A Henry, and P Price, and P C Williams
Radiation dose from kilovoltage cone beam computed tomography in an image-guided radiotherapy procedure.
February 2009, International journal of radiation oncology, biology, physics,
C J Moore, and A Amer, and T Marchant, and J R Sykes, and J Davies, and J Stratford, and C McCarthy, and C MacBain, and A Henry, and P Price, and P C Williams
Dose indices of kilovoltage cone beam computed tomography for various image guided radiotherapy protocols.
May 2023, Radiation protection dosimetry,
C J Moore, and A Amer, and T Marchant, and J R Sykes, and J Davies, and J Stratford, and C McCarthy, and C MacBain, and A Henry, and P Price, and P C Williams
Fast kilovoltage/megavoltage (kVMV) breathhold cone-beam CT for image-guided radiotherapy of lung cancer.
August 2010, Physics in medicine and biology,
C J Moore, and A Amer, and T Marchant, and J R Sykes, and J Davies, and J Stratford, and C McCarthy, and C MacBain, and A Henry, and P Price, and P C Williams
Theoretical aspects of implementation of kilovoltage cone-beam CT onboard linear accelerator for image-guided radiotherapy.
August 2009, Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico,
C J Moore, and A Amer, and T Marchant, and J R Sykes, and J Davies, and J Stratford, and C McCarthy, and C MacBain, and A Henry, and P Price, and P C Williams
Prostate image-guided radiotherapy by megavolt cone-beam CT.
August 2011, Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al],
C J Moore, and A Amer, and T Marchant, and J R Sykes, and J Davies, and J Stratford, and C McCarthy, and C MacBain, and A Henry, and P Price, and P C Williams
Advances in kilovoltage x-ray beam dosimetry.
March 2014, Physics in medicine and biology,
C J Moore, and A Amer, and T Marchant, and J R Sykes, and J Davies, and J Stratford, and C McCarthy, and C MacBain, and A Henry, and P Price, and P C Williams
Single-center outcomes of image-guided radiotherapy in the management of vertebral hemangioma with daily kilovoltage cone-beam computerized tomography.
January 2021, Journal of cancer research and therapeutics,
C J Moore, and A Amer, and T Marchant, and J R Sykes, and J Davies, and J Stratford, and C McCarthy, and C MacBain, and A Henry, and P Price, and P C Williams
Automated ultrafast kilovoltage-megavoltage cone-beam CT for image guided radiotherapy of lung cancer: System description and real-time results.
April 2018, Zeitschrift fur medizinische Physik,
Copied contents to your clipboard!