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A light and electron microscopic study was conducted to investigate nuclear changes observed in specimens obtained from various sites by computed tomographic (CT)-guided fine needle aspiration (FNA) biopsy. These changes, which consisted of a disappearance of the nuclear chromatin and a disruption of the nuclear membrane, were found in 70% of 10 FNA specimens obtained with CT guidance, in 26% of 15 specimens obtained with fluoroscopic guidance and in 0% of 10 specimens obtained without x-ray imaging techniques. Although the number of cases studied was small and the mechanisms responsible for these changes are not clear, cytopathologists should be aware of alterations in evaluating FNA specimens obtained with the guidance of x-ray imaging techniques.
K Yoneda, and
R L Mason, and
S McKinney, and
C Pulmano
February 1994,
Maryland medical journal (Baltimore, Md. : 1985),
K Yoneda, and
R L Mason, and
S McKinney, and
C Pulmano
March 2022,
Cytopathology : official journal of the British Society for Clinical Cytology,
K Yoneda, and
R L Mason, and
S McKinney, and
C Pulmano
January 2009,
Acta cytologica,
K Yoneda, and
R L Mason, and
S McKinney, and
C Pulmano
January 2009,
Acta cytologica,
K Yoneda, and
R L Mason, and
S McKinney, and
C Pulmano
November 1992,
Revista medica de Chile,
K Yoneda, and
R L Mason, and
S McKinney, and
C Pulmano
August 2013,
RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin,
K Yoneda, and
R L Mason, and
S McKinney, and
C Pulmano
August 2006,
Cancer,
K Yoneda, and
R L Mason, and
S McKinney, and
C Pulmano
February 2015,
Cancer cytopathology,
K Yoneda, and
R L Mason, and
S McKinney, and
C Pulmano
May 2010,
Journal of pathology informatics,
K Yoneda, and
R L Mason, and
S McKinney, and
C Pulmano
January 1989,
Acta cytologica,
