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A general and efficient FeCl3-catalyzed nucleophilic substitution of propargylic alcohols. 2006

Zhuang-ping Zhan, and Jing-liang Yu, and Hui-juan Liu, and Yuan-yuan Cui, and Rui-feng Yang, and Wen-zhen Yang, and Jun-ping Li
Department of Chemistry and Key Laboratory for Chemical Biology of Fujian Province, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, P. R. China. zpzhan@xmu.edu.cn

A general and efficient FeCl3-catalyzed substitution reaction of propargylic alcohols with carbon- and heteroatom-centered nucleophiles such as allyl trimethylsilane, alcohols, aromatic compounds, thiols, and amides, leading to the construction of C-C, C-O, C-S and C-N bonds, has been developed.

UI MeSH Term Description Entries
D002384 Catalysis The facilitation of a chemical reaction by material (catalyst) that is not consumed by the reaction. Catalyses
D002712 Chlorides Inorganic compounds derived from hydrochloric acid that contain the Cl- ion. Chloride,Chloride Ion Level,Ion Level, Chloride,Level, Chloride Ion
D005290 Ferric Compounds Inorganic or organic compounds containing trivalent iron. Compounds, Ferric
D000480 Alkynes Hydrocarbons with at least one triple bond in the linear portion, of the general formula Cn-H2n-2. Acetylenic Compounds,Alkyne,Acetylenes
D020005 Propanols Isomeric forms and derivatives of PROPANOL (C3H7OH). Alcohols, Propyl,Propyl Alcohols

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