-transparent.png){kind=logo}
The efficiency of the subrenal capsule assay (SRCA) was studied with fresh tissue of esophageal squamous cell carcinoma. The day-to-day changes in 10 carcinoma cases were evaluated for 9 days. The cancer cells continued to proliferate from the 3rd to the 7th day after the implantation and then decreased. The host reaction was recognized histologically from the 3rd or 4th day to the 9th day. However, the immune reaction did not significantly influence the evaluation of SRCA until the 7th day. The immunohistochemical staining with anti-bromodeoxyuridine monoclonal antibody revealed the existence of cancer cells at the DNA synthesizing stage (S stage) in the graft until the 7th day. In chemosensitivity test by SRCA, 21 patients were studied, and all were evaluable. 5-FU administration produced a response in 8/21 cases (38.1%), VDS in 8/21 (38.1%), and CDDP in 3/21 (14.3%). Used in combination, CDDP + VDS was effective in 7/18 cases (38.9%) and CDDP + BLM in 6/18 cases (33.3%).
M Sunagawa, and
T Suzuki, and
K Ito, and
M Endo
June 1989,
[Zasshi] [Journal]. Nihon Kyobu Geka Gakkai,
M Sunagawa, and
T Suzuki, and
K Ito, and
M Endo
July 1990,
Hinyokika kiyo. Acta urologica Japonica,
M Sunagawa, and
T Suzuki, and
K Ito, and
M Endo
May 1988,
Nihon Gan Chiryo Gakkai shi,
M Sunagawa, and
T Suzuki, and
K Ito, and
M Endo
April 1987,
Gan to kagaku ryoho. Cancer & chemotherapy,
M Sunagawa, and
T Suzuki, and
K Ito, and
M Endo
December 1991,
Journal of UOEH,
M Sunagawa, and
T Suzuki, and
K Ito, and
M Endo
June 1989,
Nihon Hinyokika Gakkai zasshi. The japanese journal of urology,
M Sunagawa, and
T Suzuki, and
K Ito, and
M Endo
March 1987,
Gan to kagaku ryoho. Cancer & chemotherapy,
M Sunagawa, and
T Suzuki, and
K Ito, and
M Endo
May 1990,
Nihon Sanka Fujinka Gakkai zasshi,
M Sunagawa, and
T Suzuki, and
K Ito, and
M Endo
March 1988,
Gan to kagaku ryoho. Cancer & chemotherapy,
M Sunagawa, and
T Suzuki, and
K Ito, and
M Endo
March 1988,
Gan to kagaku ryoho. Cancer & chemotherapy,
