BIOMAT Database Logo BIOMAT Database Logo

Identification of YhdA as a regulator of the Escherichia coli carbon storage regulation system. 2006

Kristina Jonas, and Henrik Tomenius, and Ute Römling, and Dimitris Georgellis, and Ojar Melefors
Swedish Institute for Infectious Disease Control, Solna, Sweden.

The Escherichia coli BarA-UvrY two-component system, which controls adaptation via the CsrB and CsrC sRNAs, is induced at the entry of the stationary phase by an unknown stimulus. Using a csrB-lacZ fusion, we demonstrated that the factors RelA, SpoT and LuxS, previously suggested to act on orthologues of this system, have no role in BarA-UvrY induction. However, using a transposon screen, we identified the hypothetical protein YhdA as a new regulator of CsrB and CsrC expression. The YhdA protein is predicted to be membrane-bound and to harbor GGDEF and EAL domains, which, however, are highly divergent from the consensus motifs.

UI MeSH Term Description Entries
D008565 Membrane Proteins Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors. Cell Membrane Protein,Cell Membrane Proteins,Cell Surface Protein,Cell Surface Proteins,Integral Membrane Proteins,Membrane-Associated Protein,Surface Protein,Surface Proteins,Integral Membrane Protein,Membrane Protein,Membrane-Associated Proteins,Membrane Associated Protein,Membrane Associated Proteins,Membrane Protein, Cell,Membrane Protein, Integral,Membrane Proteins, Integral,Protein, Cell Membrane,Protein, Cell Surface,Protein, Integral Membrane,Protein, Membrane,Protein, Membrane-Associated,Protein, Surface,Proteins, Cell Membrane,Proteins, Cell Surface,Proteins, Integral Membrane,Proteins, Membrane,Proteins, Membrane-Associated,Proteins, Surface,Surface Protein, Cell
D002244 Carbon A nonmetallic element with atomic symbol C, atomic number 6, and atomic weight [12.0096; 12.0116]. It may occur as several different allotropes including DIAMOND; CHARCOAL; and GRAPHITE; and as SOOT from incompletely burned fuel. Carbon-12,Vitreous Carbon,Carbon 12,Carbon, Vitreous
D004926 Escherichia coli A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc. Alkalescens-Dispar Group,Bacillus coli,Bacterium coli,Bacterium coli commune,Diffusely Adherent Escherichia coli,E coli,EAggEC,Enteroaggregative Escherichia coli,Enterococcus coli,Diffusely Adherent E. coli,Enteroaggregative E. coli,Enteroinvasive E. coli,Enteroinvasive Escherichia coli
D005809 Genes, Regulator Genes which regulate or circumscribe the activity of other genes; specifically, genes which code for PROTEINS or RNAs which have GENE EXPRESSION REGULATION functions. Gene, Regulator,Regulator Gene,Regulator Genes,Regulatory Genes,Gene, Regulatory,Genes, Regulatory,Regulatory Gene
D015964 Gene Expression Regulation, Bacterial Any of the processes by which cytoplasmic or intercellular factors influence the differential control of gene action in bacteria. Bacterial Gene Expression Regulation,Regulation of Gene Expression, Bacterial,Regulation, Gene Expression, Bacterial
D029968 Escherichia coli Proteins Proteins obtained from ESCHERICHIA COLI. E coli Proteins

Related Publications

Kristina Jonas, and Henrik Tomenius, and Ute Römling, and Dimitris Georgellis, and Ojar Melefors
Manipulation of the carbon storage regulator system for metabolite remodeling and biofuel production in Escherichia coli.
June 2012, Microbial cell factories,
Kristina Jonas, and Henrik Tomenius, and Ute Römling, and Dimitris Georgellis, and Ojar Melefors
Solution structure of the carbon storage regulator protein CsrA from Escherichia coli.
May 2005, Journal of bacteriology,
Kristina Jonas, and Henrik Tomenius, and Ute Römling, and Dimitris Georgellis, and Ojar Melefors
Metabolome and transcriptome-wide effects of the carbon storage regulator A in enteropathogenic Escherichia coli.
January 2019, Scientific reports,
Kristina Jonas, and Henrik Tomenius, and Ute Römling, and Dimitris Georgellis, and Ojar Melefors
A novel sRNA component of the carbon storage regulatory system of Escherichia coli.
May 2003, Molecular microbiology,
Kristina Jonas, and Henrik Tomenius, and Ute Römling, and Dimitris Georgellis, and Ojar Melefors
Identification of a Novel Regulator for the Escherichia coli fit Iron Transport System.
January 2008, The open microbiology journal,
Kristina Jonas, and Henrik Tomenius, and Ute Römling, and Dimitris Georgellis, and Ojar Melefors
The carbon storage regulator (Csr) system exerts a nutrient-specific control over central metabolism in Escherichia coli strain Nissle 1917.
January 2013, PloS one,
Kristina Jonas, and Henrik Tomenius, and Ute Römling, and Dimitris Georgellis, and Ojar Melefors
Identification of SanA as a novel regulator of peptidoglycan biogenesis in Escherichia coli.
May 2025, PLoS genetics,
Kristina Jonas, and Henrik Tomenius, and Ute Römling, and Dimitris Georgellis, and Ojar Melefors
[IHF protein as a regulator of Escherichia coli metabolism].
January 1998, Postepy biochemii,
Kristina Jonas, and Henrik Tomenius, and Ute Römling, and Dimitris Georgellis, and Ojar Melefors
Mineral Availability as a Key Regulator of Soil Carbon Storage.
May 2017, Environmental science & technology,
Kristina Jonas, and Henrik Tomenius, and Ute Römling, and Dimitris Georgellis, and Ojar Melefors
Identification of a fatty acyl responsive regulator (FarR) in Escherichia coli.
December 1994, FEBS letters,
Copied contents to your clipboard!