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Experiments on unbred male mice demonstrated qualitative differences in the pharmacological effect of substance P fragments (P1-4 and P5-11) injected intraperitoneally in a dose of 250 mcg/kg. Fragments P1-4 and P1-4 dodecylamide on the one hand, had a positive effect on the level of motivation which was displayed by lesser consumption of alcohol by the animals, and, on the other, possessed immunocorrective properties manifested by restoration of macrophage phagocytic activity and immune response to sheep erythrocytes, which were impaired by chronic alcoholic intoxication. Fragment P5-11 had no effect on alcoholic motivation and produced a directly contrary action on the immune system, it inhibited the formation of antibody-forming cells.
V A Evseev, and
T V Davydova, and
V G Fomina, and
P Oeme, and
Iu Odariuk
May 1982,
Regulatory peptides,
V A Evseev, and
T V Davydova, and
V G Fomina, and
P Oeme, and
Iu Odariuk
April 1980,
Brain research,
V A Evseev, and
T V Davydova, and
V G Fomina, and
P Oeme, and
Iu Odariuk
September 1990,
Molecular immunology,
V A Evseev, and
T V Davydova, and
V G Fomina, and
P Oeme, and
Iu Odariuk
January 1988,
Pulmonary pharmacology,
V A Evseev, and
T V Davydova, and
V G Fomina, and
P Oeme, and
Iu Odariuk
April 1982,
Die Pharmazie,
V A Evseev, and
T V Davydova, and
V G Fomina, and
P Oeme, and
Iu Odariuk
December 1998,
Neuropeptides,
V A Evseev, and
T V Davydova, and
V G Fomina, and
P Oeme, and
Iu Odariuk
January 1977,
Biochemical Society transactions,
V A Evseev, and
T V Davydova, and
V G Fomina, and
P Oeme, and
Iu Odariuk
September 2009,
Peptides,
V A Evseev, and
T V Davydova, and
V G Fomina, and
P Oeme, and
Iu Odariuk
February 1992,
Arerugi = [Allergy],
V A Evseev, and
T V Davydova, and
V G Fomina, and
P Oeme, and
Iu Odariuk
September 1990,
Brain research,
