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Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic. 2006
Laurent X Nouvel, and
Eric Kassa-Kelembho, and
Tiago Dos Vultos, and
Germain Zandanga, and
Jean Rauzier, and
Carmen Lafoz, and
Carlos Martin, and
Jesus Blazquez, and
Antoine Talarmin, and
Brigitte Gicquel
Institut Pasteur, Paris, France.
We investigated multidrug-resistant (MDR) Mycobacterium tuberculosis strains in Bangui, Central African Republic. We found 39.6% with the same spoligotype and synonymous single nucleotide polymorphism in the mutT1 gene. However, strains had different rpoB mutations responsible for rifampin resistance. MDR strains in Bangui may emerge preferentially from a single, MDR-prone family.
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