Age related effects of pesticide exposure on neurobehavioral performance of adolescent farm workers in Brazil. 2007

David A Eckerman, and Lincoln S Gimenes, and Rosane Curi de Souza, and Patricia Regina Lopes Galvão, and Paula N Sarcinelli, and Juliana R Chrisman
Universidade de Brasília, Brasília, DF, Brazil. eckerman@unb.br

Adolescents (10 to 18 years old) from a rural area in the state of Rio de Janeiro, Brazil were tested using the Behavioral Assessment and Research System (BARS) to evaluate their performance. Participants were drawn from two areas--a school serving farm children (rural N=38) and a school serving children from a city within this area (urban N=28). These children were drawn from an ongoing study being carried out by Fundação Oswaldo Cruz where rural and urban participants were matched for age, sex, and level in school. For this ongoing study, the participants had been interviewed to determine their occupational history, especially their activities that might involve exposure to pesticides. Interview responses were used to assign an exposure index to each participant. While a few BARS performance measures suggested behavioral impairments for the rural versus the urban participants, a stronger and more consistent association between BARS measures (especially impairment of tapping, digit span, and selective attention) and level of exposure to pesticides was noted when the exposure index was entered into a multiple linear regression analysis. Exposure appeared to be especially strong for the youngest participants (10-11 years old). The relationship between these behaviors and the exposure index was stronger than the relationship between behaviors and either age or sex.

UI MeSH Term Description Entries
D008297 Male Males
D009483 Neuropsychological Tests Tests designed to assess neurological function associated with certain behaviors. They are used in diagnosing brain dysfunction or damage and central nervous system disorders or injury. Aphasia Tests,Cognitive Test,Cognitive Testing,Cognitive Tests,Memory for Designs Test,Neuropsychological Testing,AX-CPT,Behavioral Assessment of Dysexecutive Syndrome,CANTAB,Cambridge Neuropsychological Test Automated Battery,Clock Test,Cognitive Function Scanner,Continuous Performance Task,Controlled Oral Word Association Test,Delis-Kaplan Executive Function System,Developmental Neuropsychological Assessment,Hooper Visual Organization Test,NEPSY,Neuropsychologic Tests,Neuropsychological Test,Paced Auditory Serial Addition Test,Repeatable Battery for the Assessment of Neuropsychological Status,Rey-Osterrieth Complex Figure,Symbol Digit Modalities Test,Test of Everyday Attention,Test, Neuropsychological,Tests, Neuropsychological,Tower of London Test,Neuropsychologic Test,Test, Cognitive,Testing, Cognitive,Testing, Neuropsychological,Tests, Cognitive
D010575 Pesticides Chemicals used to destroy pests of any sort. The concept includes fungicides (FUNGICIDES, INDUSTRIAL); INSECTICIDES; RODENTICIDES; etc. Pesticide
D011597 Psychomotor Performance The coordination of a sensory or ideational (cognitive) process and a motor activity. Perceptual Motor Performance,Sensory Motor Performance,Visual Motor Coordination,Coordination, Visual Motor,Coordinations, Visual Motor,Motor Coordination, Visual,Motor Coordinations, Visual,Motor Performance, Perceptual,Motor Performance, Sensory,Motor Performances, Perceptual,Motor Performances, Sensory,Perceptual Motor Performances,Performance, Perceptual Motor,Performance, Psychomotor,Performance, Sensory Motor,Performances, Perceptual Motor,Performances, Psychomotor,Performances, Sensory Motor,Psychomotor Performances,Sensory Motor Performances,Visual Motor Coordinations
D001938 Brazil A country located on the eastern coast of South America, located between Colombia and Peru, that borders the Atlantic Ocean. It is bordered on the north by Venezuela, Guyana, Suriname, and French Guiana, on the south by Uruguay, and on the west by Argentina. The capital is Brasilia.
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000375 Aging The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time. Senescence,Aging, Biological,Biological Aging

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