-transparent.png){kind=logo}
Synthesis of carbocyclic analogues of 4'-ethynyl- and 4'-cyano-d4T. 2004
Hiroki Kumamoto, and
Keisuke Kato, and
Kazuhiro Haraguchi, and
Hiromichi Tanaka, and
Takao Nitanda, and
Masanori Baba, and
Ginger E Dutschman, and
Yung-Chi Cheng
School of Pharmaceutical Sciences, Showa University, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan.
Synthesis of carbocyclic analogues of 4'-ethynyl and cyano-d4T (4 and 5) was investigated. The ethynyl or cyano group was constructed by conversion of the ester function of key intermediate 13. The carbocyclic unit 12 was prepared from readily available beta-keto ester 6.
Related Publications
Hiroki Kumamoto, and
Keisuke Kato, and
Kazuhiro Haraguchi, and
Hiromichi Tanaka, and
Takao Nitanda, and
Masanori Baba, and
Ginger E Dutschman, and
Yung-Chi Cheng
January 2008,
Nucleic acids symposium series (2004),
Hiroki Kumamoto, and
Keisuke Kato, and
Kazuhiro Haraguchi, and
Hiromichi Tanaka, and
Takao Nitanda, and
Masanori Baba, and
Ginger E Dutschman, and
Yung-Chi Cheng
November 2004,
The Journal of organic chemistry,
Hiroki Kumamoto, and
Keisuke Kato, and
Kazuhiro Haraguchi, and
Hiromichi Tanaka, and
Takao Nitanda, and
Masanori Baba, and
Ginger E Dutschman, and
Yung-Chi Cheng
January 2003,
Nucleosides, nucleotides & nucleic acids,
Hiroki Kumamoto, and
Keisuke Kato, and
Kazuhiro Haraguchi, and
Hiromichi Tanaka, and
Takao Nitanda, and
Masanori Baba, and
Ginger E Dutschman, and
Yung-Chi Cheng
January 1991,
Yao xue xue bao = Acta pharmaceutica Sinica,
Hiroki Kumamoto, and
Keisuke Kato, and
Kazuhiro Haraguchi, and
Hiromichi Tanaka, and
Takao Nitanda, and
Masanori Baba, and
Ginger E Dutschman, and
Yung-Chi Cheng
January 1986,
Journal of medicinal chemistry,
Hiroki Kumamoto, and
Keisuke Kato, and
Kazuhiro Haraguchi, and
Hiromichi Tanaka, and
Takao Nitanda, and
Masanori Baba, and
Ginger E Dutschman, and
Yung-Chi Cheng
January 2003,
Nucleosides, nucleotides & nucleic acids,
Hiroki Kumamoto, and
Keisuke Kato, and
Kazuhiro Haraguchi, and
Hiromichi Tanaka, and
Takao Nitanda, and
Masanori Baba, and
Ginger E Dutschman, and
Yung-Chi Cheng
January 2004,
Nucleosides, nucleotides & nucleic acids,
Hiroki Kumamoto, and
Keisuke Kato, and
Kazuhiro Haraguchi, and
Hiromichi Tanaka, and
Takao Nitanda, and
Masanori Baba, and
Ginger E Dutschman, and
Yung-Chi Cheng
October 1990,
Chemical & pharmaceutical bulletin,
Hiroki Kumamoto, and
Keisuke Kato, and
Kazuhiro Haraguchi, and
Hiromichi Tanaka, and
Takao Nitanda, and
Masanori Baba, and
Ginger E Dutschman, and
Yung-Chi Cheng
December 2022,
Organic & biomolecular chemistry,
Hiroki Kumamoto, and
Keisuke Kato, and
Kazuhiro Haraguchi, and
Hiromichi Tanaka, and
Takao Nitanda, and
Masanori Baba, and
Ginger E Dutschman, and
Yung-Chi Cheng
February 2015,
Marine drugs,
