BIOMAT Database Logo BIOMAT Database Logo

An efficient and chemoselective synthesis of N-substituted 2-aminopyridines via a microwave-assisted multicomponent reaction. 2007

Shujiang Tu, and Bo Jiang, and Yan Zhang, and Runhong Jia, and Junyong Zhang, and Changsheng Yao, and Feng Shi
Department of Chemistry, Xuzhou Normal University, Key Laboratory of Biotechnology for Medicinal Plant Xuzhou, Jiangsu, 211116, P R China. laotu@xznu.edu.cn

A facile and selective synthesis of N-substituted 2-aminopyridines is accomplished via microwave-assisted multi-component reactions controlled by the basicity of amine and the nature of solvent. In addition, a possible mechanism accounting for the reaction was proposed.

UI MeSH Term Description Entries
D008872 Microwaves That portion of the electromagnetic spectrum from the UHF (ultrahigh frequency) radio waves and extending into the INFRARED RAYS frequencies. EHF Waves,Extremely High Frequency Radio Waves,Micro Wave,Micro Waves,Ultrahigh Frequency Waves,Microwave Radiation,EHF Wave,Micro Waves,Microwave,Microwave Radiations,Radiation, Microwave,Ultrahigh Frequency Wave,Wave, EHF,Wave, Micro,Wave, Ultrahigh Frequency,Waves, Micro
D008956 Models, Chemical Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment. Chemical Models,Chemical Model,Model, Chemical
D002625 Chemistry, Organic The study of the structure, preparation, properties, and reactions of carbon compounds. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed) Organic Chemistry
D006361 Heating The application of heat to raise the temperature of the environment, ambient or local, or the systems for accomplishing this effect. It is distinguished from HEAT, the physical property and principle of physics.
D000588 Amines A group of compounds derived from ammonia by substituting organic radicals for the hydrogens. (From Grant & Hackh's Chemical Dictionary, 5th ed) Amine
D000631 Aminopyridines Pyridines substituted in any position with an amino group. May be hydrogenated but must retain at least one double bond. Aminopyridine
D012997 Solvents Liquids that dissolve other substances (solutes), generally solids, without any change in chemical composition, as, water containing sugar. (Grant & Hackh's Chemical Dictionary, 5th ed) Solvent
D013055 Spectrophotometry, Infrared Spectrophotometry in the infrared region, usually for the purpose of chemical analysis through measurement of absorption spectra associated with rotational and vibrational energy levels of molecules. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) IR Spectra,Infrared Spectrophotometry,IR Spectras,Spectra, IR
D015394 Molecular Structure The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds. Structure, Molecular,Molecular Structures,Structures, Molecular
D017550 Spectroscopy, Fourier Transform Infrared A spectroscopic technique in which a range of wavelengths is presented simultaneously with an interferometer and the spectrum is mathematically derived from the pattern thus obtained. FTIR,Fourier Transform Infrared Spectroscopy,Spectroscopy, Infrared, Fourier Transform

Related Publications

Shujiang Tu, and Bo Jiang, and Yan Zhang, and Runhong Jia, and Junyong Zhang, and Changsheng Yao, and Feng Shi
An Efficient Synthesis of Oxygen-Bridged Spirooxindoles via Microwave-Promoted Multicomponent Reaction.
April 2023, Molecules (Basel, Switzerland),
Shujiang Tu, and Bo Jiang, and Yan Zhang, and Runhong Jia, and Junyong Zhang, and Changsheng Yao, and Feng Shi
A microwave-assisted multicomponent synthesis of substituted 3,4-dihydroquinazolinones.
February 2015, Organic & biomolecular chemistry,
Shujiang Tu, and Bo Jiang, and Yan Zhang, and Runhong Jia, and Junyong Zhang, and Changsheng Yao, and Feng Shi
Highly efficient chemoselective synthesis of polysubstituted pyrroles via isocyanide-based multicomponent domino reaction.
August 2013, Organic letters,
Shujiang Tu, and Bo Jiang, and Yan Zhang, and Runhong Jia, and Junyong Zhang, and Changsheng Yao, and Feng Shi
An efficient and chemoselective synthesis of benzo[e][1,4]thiazepin-2(1H,3H,5H)-ones via a microwave-assisted multi-component reaction in water.
February 2009, Organic & biomolecular chemistry,
Shujiang Tu, and Bo Jiang, and Yan Zhang, and Runhong Jia, and Junyong Zhang, and Changsheng Yao, and Feng Shi
Microwave-assisted synthesis of new N₁,N₄-substituted thiosemicarbazones.
December 2011, Molecules (Basel, Switzerland),
Shujiang Tu, and Bo Jiang, and Yan Zhang, and Runhong Jia, and Junyong Zhang, and Changsheng Yao, and Feng Shi
Preparation of 2- and 4-arylmethyl N-substituted and N,N-disubstituted anilines via a "green", multicomponent reaction.
April 2005, Organic letters,
Shujiang Tu, and Bo Jiang, and Yan Zhang, and Runhong Jia, and Junyong Zhang, and Changsheng Yao, and Feng Shi
Efficient library synthesis of imidazoles using a multicomponent reaction and microwave irradiation.
February 2006, Molecular diversity,
Shujiang Tu, and Bo Jiang, and Yan Zhang, and Runhong Jia, and Junyong Zhang, and Changsheng Yao, and Feng Shi
Chemoselective and microwave-assisted synthesis of glycopeptoids.
November 2009, Organic letters,
Shujiang Tu, and Bo Jiang, and Yan Zhang, and Runhong Jia, and Junyong Zhang, and Changsheng Yao, and Feng Shi
Efficient one-pot synthesis of substituted pyridines through multicomponent reaction.
June 2010, Organic & biomolecular chemistry,
Shujiang Tu, and Bo Jiang, and Yan Zhang, and Runhong Jia, and Junyong Zhang, and Changsheng Yao, and Feng Shi
2-Aminopyridines via reaction of pyridine N-oxides and activated isocyanides.
March 2014, The Journal of organic chemistry,
Copied contents to your clipboard!