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This report describes the resistance of 537 Salmonella typhi isolates identified in Egypt between 1990-1994. Results indicated a high isolation rate for multiple resistant S. typhi (> 71% of isolates collected in 1992-93), particularly to the three standard drug regimens of the clinically relevant antibiotics; ampicillin, chloramphenicol and trimethoprim-sulfamethoxazole. This adds to the complexity and difficulty of treating infections caused by these organisms. Resistance of S. typhi was associated with a transferable 120 MD plasmid. The organism was sensitive to amikacin, aztreonam, cephalothin, ceftriaxone, gentamicin and nalidixic acid, suggesting the use of aztreonam and ceftriaxone as alternative therapeutic drugs for the treatment of multidrug-resistant S. typhi. These results may provide a clinically useful evaluation of the spread and acquisition of resistance among S. typhi strains in Egypt.
M O Wasfy, and
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Z S Mohran, and
T F Ismail, and
S H El-Etr, and
B A Oyofo
January 1994,
The Journal of antimicrobial chemotherapy,
M O Wasfy, and
D A Moustafa, and
A M El-Gendy, and
Z S Mohran, and
T F Ismail, and
S H El-Etr, and
B A Oyofo
January 1978,
Revista latinoamericana de microbiologia,
M O Wasfy, and
D A Moustafa, and
A M El-Gendy, and
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S H El-Etr, and
B A Oyofo
April 2022,
Archives of Razi Institute,
M O Wasfy, and
D A Moustafa, and
A M El-Gendy, and
Z S Mohran, and
T F Ismail, and
S H El-Etr, and
B A Oyofo
January 1983,
Annales de microbiologie,
M O Wasfy, and
D A Moustafa, and
A M El-Gendy, and
Z S Mohran, and
T F Ismail, and
S H El-Etr, and
B A Oyofo
September 1990,
The Journal of infectious diseases,
M O Wasfy, and
D A Moustafa, and
A M El-Gendy, and
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T F Ismail, and
S H El-Etr, and
B A Oyofo
April 2024,
Cureus,
M O Wasfy, and
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A M El-Gendy, and
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T F Ismail, and
S H El-Etr, and
B A Oyofo
August 2008,
Journal of infection in developing countries,
M O Wasfy, and
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A M El-Gendy, and
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T F Ismail, and
S H El-Etr, and
B A Oyofo
March 1966,
The Indian journal of medical research,
M O Wasfy, and
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A M El-Gendy, and
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T F Ismail, and
S H El-Etr, and
B A Oyofo
November 1991,
Enfermedades infecciosas y microbiologia clinica,
M O Wasfy, and
D A Moustafa, and
A M El-Gendy, and
Z S Mohran, and
T F Ismail, and
S H El-Etr, and
B A Oyofo
April 2003,
Antimicrobial agents and chemotherapy,
