[Clinical evaluation of nonseminomatous testicular germ cell tumors]. 1991

M Nukui, and M Nakao, and S Nakagawa, and H Takada, and K Ebisui, and K Sugimoto, and H Watanabe, and M Maekawa
Department of Urology, Kyoto Prefectural University of Medicine.

We treated 26 patients with nonseminomatous germ cell tumors (NSGCT) between January 1976 and March 1989. Histologically, 7 were embryonal carcinoma (27%), 4 were teratoma (15%), 2 were yolk sac tumor (8%), 10 were teratocarcinoma (38%) and 3 were other mixed tumors. As regards staging, 18 belonged to stage I (69%), 1 to stage II A (4%), 1 to stage IIB (4%), 1 to stage IIIA, 2 to stage III B1 (8%) and 3 to stage III B2 (12%). Patients in stage I were treated by orchidectomy with lymphadenectomy and occasionally chemotherapy before 1984, resulting in a 100% 5-year survival. However, after 1985, 5 cases in stage I were treated by orchidectomy alone according to a watch-and-see policy. Two cases among them relapsed within two years and both of them contained immature teratoma elements. Six patients with metastatic tumor were treated with PVB therapy of which response rate was 66.7%. The total 5-year survival rate of patients in stage I, II and III was 100%, 50%, 50%, respectively and that in overall cases was 84.6%.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009367 Neoplasm Staging Methods which attempt to express in replicable terms the extent of the neoplasm in the patient. Cancer Staging,Staging, Neoplasm,Tumor Staging,TNM Classification,TNM Staging,TNM Staging System,Classification, TNM,Classifications, TNM,Staging System, TNM,Staging Systems, TNM,Staging, Cancer,Staging, TNM,Staging, Tumor,System, TNM Staging,Systems, TNM Staging,TNM Classifications,TNM Staging Systems
D009373 Neoplasms, Germ Cell and Embryonal Neoplasms composed of primordial GERM CELLS of embryonic GONADS or of elements of the germ layers of the EMBRYO, MAMMALIAN. The concept does not refer to neoplasms located in the gonads or present in an embryo or FETUS. Germ Cell Cancer,Germ Cell Tumor,Neoplasms, Embryonal and Mixed,Cancer, Embryonal,Cancer, Embryonal and Mixed,Embryonal Neoplasms,Germ Cell Neoplasms,Germ Cell and Embryonal Neoplasms,Germ Cell and Embryonic Neoplasms,Neoplasms, Embryonal,Neoplasms, Germ Cell,Neoplasms, Germ Cell and Embryonic,Cancer, Germ Cell,Cancers, Embryonal,Cancers, Germ Cell,Embryonal Cancer,Embryonal Cancers,Embryonal Neoplasm,Germ Cell Cancers,Germ Cell Tumors,Neoplasm, Embryonal,Tumor, Germ Cell,Tumors, Germ Cell
D009919 Orchiectomy The surgical removal of one or both testicles. Castration, Male,Orchidectomy,Castrations, Male,Male Castration,Male Castrations,Orchidectomies,Orchiectomies
D011379 Prognosis A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations. Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D001761 Bleomycin A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2. It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. BLEO-cell,Blanoxan,Blenoxane,Bleolem,Bleomicina,Bleomycin A(2),Bleomycin A2,Bleomycin B(2),Bleomycin B2,Bleomycin Sulfate,Bleomycins,Bleomycinum Mack,Bléomycine Bellon,BLEO cell,BLEOcell,Bellon, Bléomycine,Mack, Bleomycinum,Sulfate, Bleomycin
D002945 Cisplatin An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle. Platinum Diamminodichloride,cis-Diamminedichloroplatinum(II),cis-Dichlorodiammineplatinum(II),Biocisplatinum,Dichlorodiammineplatinum,NSC-119875,Platidiam,Platino,Platinol,cis-Diamminedichloroplatinum,cis-Platinum,Diamminodichloride, Platinum,cis Diamminedichloroplatinum,cis Platinum
D003131 Combined Modality Therapy The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used. Multimodal Treatment,Therapy, Combined Modality,Combined Modality Therapies,Modality Therapies, Combined,Modality Therapy, Combined,Multimodal Treatments,Therapies, Combined Modality,Treatment, Multimodal,Treatments, Multimodal
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

M Nukui, and M Nakao, and S Nakagawa, and H Takada, and K Ebisui, and K Sugimoto, and H Watanabe, and M Maekawa
June 1987, Nihon Hinyokika Gakkai zasshi. The japanese journal of urology,
M Nukui, and M Nakao, and S Nakagawa, and H Takada, and K Ebisui, and K Sugimoto, and H Watanabe, and M Maekawa
October 1993, Cancer genetics and cytogenetics,
M Nukui, and M Nakao, and S Nakagawa, and H Takada, and K Ebisui, and K Sugimoto, and H Watanabe, and M Maekawa
August 2000, Oncogene,
M Nukui, and M Nakao, and S Nakagawa, and H Takada, and K Ebisui, and K Sugimoto, and H Watanabe, and M Maekawa
June 2015, Urologic oncology,
M Nukui, and M Nakao, and S Nakagawa, and H Takada, and K Ebisui, and K Sugimoto, and H Watanabe, and M Maekawa
September 2015, World journal of urology,
M Nukui, and M Nakao, and S Nakagawa, and H Takada, and K Ebisui, and K Sugimoto, and H Watanabe, and M Maekawa
January 2006, Oncology,
M Nukui, and M Nakao, and S Nakagawa, and H Takada, and K Ebisui, and K Sugimoto, and H Watanabe, and M Maekawa
August 1993, Cancer,
M Nukui, and M Nakao, and S Nakagawa, and H Takada, and K Ebisui, and K Sugimoto, and H Watanabe, and M Maekawa
January 1985, Acta urologica Belgica,
M Nukui, and M Nakao, and S Nakagawa, and H Takada, and K Ebisui, and K Sugimoto, and H Watanabe, and M Maekawa
February 1994, Urology,
M Nukui, and M Nakao, and S Nakagawa, and H Takada, and K Ebisui, and K Sugimoto, and H Watanabe, and M Maekawa
November 1998, International journal of urology : official journal of the Japanese Urological Association,
Copied contents to your clipboard!