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We studied the prevalence of antibodies against hepatitis C virus (anti-HCV) among 530 household contacts of 225 anti-HCV-positive subjects (index cases). Twenty-six (4.9%) relatives had anti-HCV, a proportion higher than that found among blood donors (175 of 22,435; 0.78%) (p less than 0.001). We did not find any differences regarding the type of relation with the index case (sexual or nonsexual). The prevalence of anti-HCV increased with the age of the relatives, with the contact time with the index case, and with the time of exposure to HCV. On the other hand, the anti-HCV was associated mainly with the existence of cirrhosis or hepatocellular carcinoma in the patient. We concluded that intrafamilial transmission may be an important mechanism in the spread of HCV.
S Riestra Menéndez, and
M Rodríguez García, and
F Sánchez San Román, and
F Menéndez Tévar, and
A Suárez González, and
C Alvarez Navascués, and
R Pérez Alvarez, and
L Rodrigo Sáez
June 1991,
Transfusion,
S Riestra Menéndez, and
M Rodríguez García, and
F Sánchez San Román, and
F Menéndez Tévar, and
A Suárez González, and
C Alvarez Navascués, and
R Pérez Alvarez, and
L Rodrigo Sáez
January 1994,
Scandinavian journal of infectious diseases,
S Riestra Menéndez, and
M Rodríguez García, and
F Sánchez San Román, and
F Menéndez Tévar, and
A Suárez González, and
C Alvarez Navascués, and
R Pérez Alvarez, and
L Rodrigo Sáez
January 1992,
Archives of virology. Supplementum,
S Riestra Menéndez, and
M Rodríguez García, and
F Sánchez San Román, and
F Menéndez Tévar, and
A Suárez González, and
C Alvarez Navascués, and
R Pérez Alvarez, and
L Rodrigo Sáez
April 1998,
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S Riestra Menéndez, and
M Rodríguez García, and
F Sánchez San Román, and
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C Alvarez Navascués, and
R Pérez Alvarez, and
L Rodrigo Sáez
January 2014,
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S Riestra Menéndez, and
M Rodríguez García, and
F Sánchez San Román, and
F Menéndez Tévar, and
A Suárez González, and
C Alvarez Navascués, and
R Pérez Alvarez, and
L Rodrigo Sáez
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S Riestra Menéndez, and
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F Sánchez San Román, and
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A Suárez González, and
C Alvarez Navascués, and
R Pérez Alvarez, and
L Rodrigo Sáez
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Journal of gastroenterology and hepatology,
S Riestra Menéndez, and
M Rodríguez García, and
F Sánchez San Román, and
F Menéndez Tévar, and
A Suárez González, and
C Alvarez Navascués, and
R Pérez Alvarez, and
L Rodrigo Sáez
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S Riestra Menéndez, and
M Rodríguez García, and
F Sánchez San Román, and
F Menéndez Tévar, and
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C Alvarez Navascués, and
R Pérez Alvarez, and
L Rodrigo Sáez
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S Riestra Menéndez, and
M Rodríguez García, and
F Sánchez San Román, and
F Menéndez Tévar, and
A Suárez González, and
C Alvarez Navascués, and
R Pérez Alvarez, and
L Rodrigo Sáez
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Medicina clinica,
