BIOMAT Database Logo BIOMAT Database Logo

Juvenile rheumatoid arthritis of the knee: MR evaluation with Gd-DOTA. 1992

C M Hervé-Somma, and G H Sebag, and A M Prieur, and V Bonnerot, and D P Lallemand
Department of Pediatric Radiology, Hopital des Enfants Malades, Paris, France.

Synovial hypertrophy, effusion, and articular cartilage status were evaluated with gadolinium tetraazacyclododecanetetraacetic acid (DOTA)-enhanced magnetic resonance (MR) imaging in 24 knees in 24 pediatric patients (17 female, seven male; mean age, 10 years; range, 3-18 years) with juvenile rheumatoid arthritis (JRA). T1-weighted spin-echo sequences were performed with a 0.5-T unit before and immediately after injection of Gd-DOTA (0.1 mmol/kg). Substantial enhancement of synovial proliferation was seen in 23 of 24 knees, allowing precise assessment of pannus extension (n = 23), joint effusion (n = 21), cartilage loss (n = 21), and meniscal hypotrophy (n = 23). On T1-weighted images without contrast enhancement, cartilage thickness, loculation of joint effusion, and pannus extension were underestimated. Thus, Gd-DOTA-enhanced MR imaging is mandatory in the assessment of knee involvement in children with JRA and may prove to be useful in the evaluation of response to therapy.

UI MeSH Term Description Entries
D007717 Knee A region of the lower extremity immediately surrounding and including the KNEE JOINT.
D007719 Knee Joint A synovial hinge connection formed between the bones of the FEMUR; TIBIA; and PATELLA. Superior Tibiofibular Joint,Joint, Knee,Joint, Superior Tibiofibular,Knee Joints,Superior Tibiofibular Joints,Tibiofibular Joint, Superior
D008279 Magnetic Resonance Imaging Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques. Chemical Shift Imaging,MR Tomography,MRI Scans,MRI, Functional,Magnetic Resonance Image,Magnetic Resonance Imaging, Functional,Magnetization Transfer Contrast Imaging,NMR Imaging,NMR Tomography,Tomography, NMR,Tomography, Proton Spin,fMRI,Functional Magnetic Resonance Imaging,Imaging, Chemical Shift,Proton Spin Tomography,Spin Echo Imaging,Steady-State Free Precession MRI,Tomography, MR,Zeugmatography,Chemical Shift Imagings,Echo Imaging, Spin,Echo Imagings, Spin,Functional MRI,Functional MRIs,Image, Magnetic Resonance,Imaging, Magnetic Resonance,Imaging, NMR,Imaging, Spin Echo,Imagings, Chemical Shift,Imagings, Spin Echo,MRI Scan,MRIs, Functional,Magnetic Resonance Images,Resonance Image, Magnetic,Scan, MRI,Scans, MRI,Shift Imaging, Chemical,Shift Imagings, Chemical,Spin Echo Imagings,Steady State Free Precession MRI
D008297 Male Males
D009942 Organometallic Compounds A class of compounds of the type R-M, where a C atom is joined directly to any other element except H, C, N, O, F, Cl, Br, I, or At. (Grant & Hackh's Chemical Dictionary, 5th ed) Metallo-Organic Compound,Metallo-Organic Compounds,Metalloorganic Compound,Organometallic Compound,Metalloorganic Compounds,Compound, Metallo-Organic,Compound, Metalloorganic,Compound, Organometallic,Compounds, Metallo-Organic,Compounds, Metalloorganic,Compounds, Organometallic,Metallo Organic Compound,Metallo Organic Compounds
D011446 Prospective Studies Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group. Prospective Study,Studies, Prospective,Study, Prospective
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D003287 Contrast Media Substances used to allow enhanced visualization of tissues. Radiopaque Media,Contrast Agent,Contrast Agents,Contrast Material,Contrast Materials,Radiocontrast Agent,Radiocontrast Agents,Radiocontrast Media,Agent, Contrast,Agent, Radiocontrast,Agents, Contrast,Agents, Radiocontrast,Material, Contrast,Materials, Contrast,Media, Contrast,Media, Radiocontrast,Media, Radiopaque
D005069 Evaluation Studies as Topic Works about studies that determine the effectiveness or value of processes, personnel, and equipment, or the material on conducting such studies. Critique,Evaluation Indexes,Evaluation Methodology,Evaluation Report,Evaluation Research,Methodology, Evaluation,Pre-Post Tests,Qualitative Evaluation,Quantitative Evaluation,Theoretical Effectiveness,Use-Effectiveness,Critiques,Effectiveness, Theoretical,Evaluation Methodologies,Evaluation Reports,Evaluation, Qualitative,Evaluation, Quantitative,Evaluations, Qualitative,Evaluations, Quantitative,Indexes, Evaluation,Methodologies, Evaluation,Pre Post Tests,Pre-Post Test,Qualitative Evaluations,Quantitative Evaluations,Report, Evaluation,Reports, Evaluation,Research, Evaluation,Test, Pre-Post,Tests, Pre-Post,Use Effectiveness
D005260 Female Females

Related Publications

C M Hervé-Somma, and G H Sebag, and A M Prieur, and V Bonnerot, and D P Lallemand
Juvenile rheumatoid arthritis of the knee: evaluation with US.
February 1994, Radiology,
C M Hervé-Somma, and G H Sebag, and A M Prieur, and V Bonnerot, and D P Lallemand
Intraarticular diffusion of Gd-DOTA after intravenous injection in the knee: MR imaging evaluation.
July 1993, Radiology,
C M Hervé-Somma, and G H Sebag, and A M Prieur, and V Bonnerot, and D P Lallemand
Knee in early juvenile rheumatoid arthritis: MR imaging findings.
September 2001, Radiology,
C M Hervé-Somma, and G H Sebag, and A M Prieur, and V Bonnerot, and D P Lallemand
MR imaging of the knee in acute rheumatoid arthritis: synovial uptake of gadolinium-DOTA.
August 1990, AJR. American journal of roentgenology,
C M Hervé-Somma, and G H Sebag, and A M Prieur, and V Bonnerot, and D P Lallemand
MR evaluation of the temporomandibular joint in juvenile rheumatoid arthritis.
January 1993, Journal of computer assisted tomography,
C M Hervé-Somma, and G H Sebag, and A M Prieur, and V Bonnerot, and D P Lallemand
Juvenile rheumatoid arthritis: assessment with MR imaging.
October 1987, Radiology,
C M Hervé-Somma, and G H Sebag, and A M Prieur, and V Bonnerot, and D P Lallemand
MR imaging in juvenile rheumatoid arthritis.
April 1988, AJR. American journal of roentgenology,
C M Hervé-Somma, and G H Sebag, and A M Prieur, and V Bonnerot, and D P Lallemand
Juvenile rheumatoid arthritis of the knee: evaluation with contrast-enhanced color Doppler ultrasound.
July 2001, Pediatric radiology,
C M Hervé-Somma, and G H Sebag, and A M Prieur, and V Bonnerot, and D P Lallemand
Rheumatoid arthritis: evaluation of hypervascular and fibrous pannus with dynamic MR imaging enhanced with Gd-DTPA.
August 1990, Radiology,
C M Hervé-Somma, and G H Sebag, and A M Prieur, and V Bonnerot, and D P Lallemand
MR imaging of rat brain glioma: Gd-DTPA versus Gd-DOTA.
March 1988, Radiology,
Copied contents to your clipboard!