The cor tical vascular blood flow pattern is associated with the functional response in cerebral cortex. The pattern of the vascular blood flow can be used to study the spatiotemporal activities of the somatosensory center and the diagnosis of the focal stroke or ischemia. In this present study, tempor al laser speckle analysis is used to obtain the cortical blood flow information. By centerline modeling method based on ridge tracking, we extracted the cortical vessels. By fusing with the laser speckle contrast results, we obtained the image of the cortical vascular blood flow pattern in which both the vessels and the blood velocity can be visualized.